Protein Alignment Eif4e and eIF4E4

DIOPT Version :10

• Sequence 1: XP_006501056.1
• Gene: Eif4e / 13684
• MGIID: 95305
• Length: 230
• Species: Mus musculus
• Sequence 2: NP_648052.1
• Gene: eIF4E4 / 38743
• FlyBaseID: FBgn0035709
• Length: 229
• Species: Drosophila melanogaster
• Alignment Length: 223
• Identity: 100/223 - (44%)
• Similarity: 141/223 - (63%)
• Gaps: 8/223 - (3%)

Mouse    13 KMATVEPETTPTTNPPPAEEEKTESNQEVANP-----EHYIKHPLQNRWALWFFKNDKSKTWQAN 72
            ||.....||...:....:|:.||.|:.::..|     :..:||||:|.|.||:.:||:||.|:..
  Fly    10 KMMDNGTETLADSPSSSSEDLKTLSDMDIRKPVTEIVDLRLKHPLENTWTLWYLENDRSKNWEDM 74

Mouse    73 LRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRS 137
            ...|:.||.|||||:|||||:..|.:..|.||||||.||:|||||:.||.||||:|.:.:.. ::
  Fly    75 QNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVINMGRGS-KA 138

Mouse   138 DLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGL 202
            :||:.||:.||.||||:|:: :::|||||:|:|.|.:||:|||....|..||..||...::.|.|
  Fly   139 ELDKLWLDVLLILIGEAFEN-TEEVCGAVINLRGKSNKISIWTANGHNELAVMEIGLKLRDLLVL 202

Mouse   203 PPKIVIGYQSHADTATKSGSTTKNRFVV 230
            ||. .:.||.|.||..|.||..|..:.|
  Fly   203 PPH-QLQYQLHKDTMCKQGSVIKAVYCV 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eif4e	XP_006501056.1	IF4E	51..210	CDD:460281	79/158 (50%)
eIF4E4	NP_648052.1	IF4E	53..209	CDD:460281	79/158 (50%)