DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Egr4 and btd

DIOPT Version :9

Sequence 1:	NP_065621.1	Gene:	Egr4 / 13656	MGIID:	99252	Length:	478	Species:	Mus musculus
Sequence 2:	NP_511100.1	Gene:	btd / 31912	FlyBaseID:	FBgn0000233	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	357	Identity:	98/357 - (27%)
Similarity:	134/357 - (37%)	Gaps:	100/357 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse   181 LRAPPASPALDAAASAFKGPY---APWEL----LSAGVPGNCGSQGSFQTTPEARFSAVGTKVED 238
            |.|||:.....:.:|:...|.   .|.:|    ..|...|......|.|:.|.:
  Fly    99 LSAPPSLSGSSSGSSSGSSPLYGKPPMKLELPYPQASSTGTASPNSSIQSAPSS----------- 152

Mouse   239 LLSISCPAELPGPA---ARLYQAGAYDTFSLAP------GDLGEGTEGLPALLTPPGGEGGSGGE 294
             .|:| |:..|.||   |.:..:.:..|.:|||      |.|.    |.|...:|    ..|...
  Fly   153 -ASVS-PSIFPSPAQSFASISASPSTPTTTLAPPTTAAAGALA----GSPTSSSP----SSSAAS 207

Mouse   295 GGEFLAAPPAQLSPLGLRGAATADFS--------KPLVADLP--------GGSGVAAPSSPA--- 340
            .....||..|..:.||....|:|.:.        .|..:..|        .|:.|...||.|
  Fly   208 AAAAAAAAAAAAADLGAAAVASAAYGWNTAYSGLGPARSQFPYAQYASDYYGNAVGMSSSAAWFS 272

Mouse   341 -----------ASFPA------AKARRKGRRGGKCSARCFCPR---------PHV-------KAF 372
                       .|:|.      |...:..||    |.||.||.         |.|       |..
  Fly   273 HQERLYQPWSSQSYPGFNFDDIAFQTQLQRR----SVRCTCPNCTNEMSGLPPIVGPDERGRKQH 333

Mouse   373 ACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGR 437
            .|.:..|.|.:.::..|..|||.|||.:||.|..|.:.|||||.|..|.||||..:|:||.:|.:
  Fly   334 ICHIPGCERLYGKASHLKTHLRWHTGERPFLCLTCGKRFSRSDELQRHGRTHTNYRPYACPICSK 398

Mouse   438 RFARSDEKKRHSKVHLKQK-------ARAEER 462
            :|:|||...:|.|.|.|.|       |.|:|:
  Fly   399 KFSRSDHLSKHKKTHFKDKKSKKVLAAEAKEQ 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Egr4	NP_065621.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..302		5/26 (19%)
		zf-C2H2	372..396	CDD:278523	7/23 (30%)
		C2H2 Zn finger	374..396	CDD:275368	7/21 (33%)
		zf-H2C2_2	388..413	CDD:290200	12/24 (50%)
		COG5048	400..>458	CDD:227381	28/64 (44%)
		C2H2 Zn finger	404..424	CDD:275368	10/19 (53%)
		zf-H2C2_2	416..441	CDD:290200	11/24 (46%)
		C2H2 Zn finger	432..452	CDD:275368	8/19 (42%)
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	6/18 (33%)
		zf-H2C2_2	349..374	CDD:290200	12/24 (50%)
		C2H2 Zn finger	365..385	CDD:275368	10/19 (53%)
		zf-H2C2_2	377..402	CDD:290200	11/24 (46%)
		zf-C2H2	391..413	CDD:278523	9/21 (43%)
		C2H2 Zn finger	393..413	CDD:275368	8/19 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I4686
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960