DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Egr3 and odd

DIOPT Version :9

Sequence 1:	NP_061251.1	Gene:	Egr3 / 13655	MGIID:	1306780	Length:	387	Species:	Mus musculus
Sequence 2:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	286	Identity:	77/286 - (26%)
Similarity:	105/286 - (36%)	Gaps:	72/286 - (25%)

- Green bases have known domain annotations that are detailed below.

Mouse   131 QPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGL----AYSPQDYQSAKPALDSNLFPMI 191
            |..|......||..|..|      ::||:.|....|..:    .|..|..|...|
  Fly   103 QQQQHQAPQQYPVYPTAS------ADPVAVHQQLMNHWIRNAAIYQQQQQQQQHP---------- 151

Mouse   192 PDYNLYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQPPLTLK-- 254
                  ||.:..|.  .|.|..  .|..|.|.| ..|.::.|   ..:...||::|    |||
  Fly   152 ------HHHHHHGH--PHHPHP--HPHHVRPYP-AGLHSLHA---AVMGRHFGAMP----TLKLG 198

Mouse   255 --------------PIRPR-----KYPNRP----------SKTPLHERPHACPAEGCDRRFSRSD 290
                          ..||:     ||.||.          .:|...|||::|  :.|.:.|.|.|
  Fly   199 GAGGASGVPSGATGSSRPKKQFICKYCNRQFTKSYNLLIHERTHTDERPYSC--DICGKAFRRQD 261

Mouse   291 ELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIH 355
            .|..|..||:..|||:|..|.:.|.:|..|..|..||..|.|..|..|.|.|.:....|.|.:.|
  Fly   262 HLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVHKVTHLEEGPHKCPICQRSFNQRANLKSHLQSH 326

Mouse   356 LKQKEKKSEKGGAPSAS-SAPTVSLA 380
            .:|..|:.....:|:.| |.|..:|:
  Fly   327 SEQSTKEVVVTTSPATSHSVPNQALS 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Egr3	NP_061251.1	DUF3446	87..147	CDD:314753	5/15 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	241..283		17/72 (24%)
		COG5048	269..>333	CDD:227381	24/63 (38%)
		C2H2 Zn finger	277..299	CDD:275368	7/21 (33%)
		COG5048	303..>375	CDD:227381	25/72 (35%)
		C2H2 Zn finger	307..327	CDD:275368	6/19 (32%)
		C2H2 Zn finger	335..355	CDD:275368	6/19 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	348..387		10/34 (29%)
odd	NP_722922.1	COG5048	<203..334	CDD:227381	41/132 (31%)
		C2H2 Zn finger	222..242	CDD:275368	4/19 (21%)
		zf-H2C2_2	234..259	CDD:290200	7/26 (27%)
		C2H2 Zn finger	250..270	CDD:275368	7/21 (33%)
		zf-H2C2_2	262..285	CDD:290200	9/22 (41%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		zf-C2H2	304..326	CDD:278523	6/21 (29%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030