Protein Alignment CPB2 and CG18417

DIOPT Version :10

• Sequence 1: NP_001863.3
• Gene: CPB2 / 1361
• HGNCID: 2300
• Length: 423
• Species: Homo sapiens
• Sequence 2: NP_648119.1
• Gene: CG18417 / 38829
• FlyBaseID: FBgn0035780
• Length: 427
• Species: Drosophila melanogaster
• Alignment Length: 423
• Identity: 123/423 - (29%)
• Similarity: 205/423 - (48%)
• Gaps: 28/423 - (6%)

Human    20 VFAFQSGQVLAALPRTSR-QVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFF--VNASDVDNVK 81
            :.|.....:.|.|.||:: :...:..:::....|.:....::|:........|  :||.:...:.
  Fly     7 ILALSCLSLSAGLQRTNKYEGYKIYEVSSEARSVAFSEALSELVKNASYYEVFSELNAGNPGKIM 71

Human    82 AH----------LNVSGIPCSVLLADVEDLIQQQISNDTV----SPRASASYYEQYHSLNEIYSW 132
            .|          :..:.:...::..:|...:.:|...:.:    .|.......|:|::..||..:
  Fly    72 VHPHEQVNFVQLMEENNVKYDIINRNVGLTLSRQFETNRMLRHWFPYNGRLGTERYYNHEEINQF 136

Human   133 IEFITERHPDMLTKIHIGSSFEKYPLYVLKV-SGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196
            ||.:...||..:....:|.|:|...|..:.: :|..:..||.|.:|.|.|||||||||...:.|.
  Fly   137 IEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDGGFHAREWISPAAATYLIN 201

Human   197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSW--KKNRMWRKNRSFYANNHCIGTDLNRNF 259
            .:.  |. :....:||...|:.::||||.|||:|:.  :..|||||.|. .:::.|||||.||||
  Fly   202 QLV--YN-LEDNADLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRKTRK-PSSSDCIGTDPNRNF 262

Human   260 ASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTR 324
             ..||.|||||...|...|.|..|.||||...|...:...:::.:.|:::|||...|::|:.:|.
  Fly   263 -DFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQMYLTLHSYGSLILYPWGWTA 326

Human   325 SKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETL-YLAPGGGDDWIYDLGIKYSFTIELRD 388
            :.....|:|..||:....||:: :..|.|..|..:.|: |.|.|..||:.::.|...|||:||..
  Fly   327 AVPDTEEDLHEVAAAGQSAIQE-ATGTIYKIGPSATTINYAASGASDDYAFNAGFPISFTMELPF 390

Human   389 TGTYGFLLPERYIKPTCREAFAAVSKIAWHVIR 421
            .|| ||..|...|....:|.:..::.:|..||:
  Fly   391 GGT-GFDPPASDIDSIVKETWVGIAAMARKVIQ 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPB2	NP_001863.3	Propep_M14	33..105	CDD:460505	9/84 (11%)
		M14_CPB2	119..420	CDD:349465	107/304 (35%)
CG18417	NP_648119.1	Propep_M14	<70..105	CDD:460505	2/34 (6%)
		Peptidase_M14	133..412	CDD:459730	103/285 (36%)