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Protein Alignment CPB2 and CG8945

DIOPT Version :9

Sequence 1:	NP_001863.3	Gene:	CPB2 / 1361	HGNCID:	2300	Length:	423	Species:	Homo sapiens
Sequence 2:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	133/463 - (28%)
Similarity:	215/463 - (46%)	Gaps:	89/463 - (19%)

- Green bases have known domain annotations that are detailed below.

Human    22 AFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPV-------TADLIVKKKQVHFFVNASDVDN 79
            ::...|:....|:...||:.|:......:.|..|.:       ..|::|..|.:..|
  Fly   980 SYDKYQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLRGLTDVLVPPKMLVDF-------- 1036

Human    80 VKAHLNVSGIPCSVLLADVEDLIQQQISNDTV-------SPRASA---SYYEQYHSLNEIYSWIE 134
             :..||..||...||:.||...|..:::.:..       .||.:|   ..:.:||:.:||..::|
  Fly  1037 -QGTLNYEGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLE 1100

Human   135 FITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAA---------------------KNAIWIDC 178
            .:..|||.::..||||.|||..||.|:|:..|:.||                     .||::::.
  Fly  1101 TVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEA 1165

Human   179 GIHAREWISPAFCLWFIGHITQFYGIIGQYTN-------LLRLVDFYVMPVVNVDGYDYSWKKNR 236
            |.....||.||...|.|..:.:.     ..||       .:|...:|:|||:|.|||.||.:.:|
  Fly  1166 GAQGLAWIGPAAATWMIAELLRL-----MKTNKSNEDVEFIRNTTWYIMPVLNPDGYAYSHEYDR 1225

Human   237 MWRKNRSFY---------------------ANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCG 280
            .|:|:||.:                     .:..|.|.||:||:. .||.:.|:|.:.|:|.|.|
  Fly  1226 FWKKSRSQHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWL-YHWGKRGSSKAPCNEFYAG 1289

Human   281 LYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPY----SYTRSKSKDHEELSLVASEAV 341
            ..|.||||.|||:.||.....|||.|||:.:|.|.|.:|.    ::...:..|..::::|.::.:
  Fly  1290 PAPFSEPETKAVSEFLMDYRTQIKLYISLQAYGQVISYPVKANSTFNSERLDDFLDVAMVGTDGL 1354

Human   342 RAIEKISKNTRYTHGHGSETLYLAPGGGDDW-IYDLGIKYSFTIELRDTGTYGFLLPERYIKPTC 405
            |   |....:||.....::.:....|..|.: .|::||.:|:|::|.|.|.:|:|||...|:||.
  Fly  1355 R---KKGSKSRYKVDASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTA 1416

Human   406 REAFAAVS 413
            |:||..:|
  Fly  1417 RDAFEIIS 1424

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.