DRSC/TRiP Functional Genomics Resources

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Protein Alignment CPB2 and CG32379

DIOPT Version :9

Sequence 1:NP_001863.3 Gene:CPB2 / 1361 HGNCID:2300 Length:423 Species:Homo sapiens
Sequence 2:NP_729252.2 Gene:CG32379 / 326211 FlyBaseID:FBgn0052379 Length:344 Species:Drosophila melanogaster


Alignment Length:346 Identity:107/346 - (30%)
Similarity:168/346 - (48%) Gaps:32/346 - (9%)


- Green bases have known domain annotations that are detailed below.


Human    93 VLLADVEDLIQQQISN-------------DTVSPRASASYYEQYHSLNEIYSWIEFITERHPDML 144
            ||:.|:..|:..|.:.             |.:|         .:::.:||..:::.:.||.|..:
  Fly    10 VLIEDLAPLVHAQRAENLRKKLLIQWPHIDVLS---------AFYTHSEINDYLDSLLERFPKRV 65

Human   145 TKIHIGSSFEKYPLYVLKV-SGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQY 208
            .....|.|:|:.||.||.: :|..:..|..|.||..:||||||||:..|:.|..:...|   |..
  Fly    66 QVKQFGWSYERRPLKVLTITNGDGRRNKPVILIDGTVHAREWISPSMALYIIQQLLDNY---GDN 127

Human   209 TNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSS 273
            ..||:..|:.:|||||.|||:|:...:|.|||:|...:|..|||||:||||..:...:||:||..
  Fly   128 QELLQDYDWVIMPVVNADGYEYTHTDSRYWRKSRRPTSNPECIGTDINRNFGYEWGHDEGSSSDP 192

Human   274 CSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVAS 338
            |...|.|..|..:.|.:.:...:.....::..|:|:|||..:.:.|:.||......::::..||.
  Fly   193 CENIYRGERPFDQSESQVLRDVMLHYKGRLNFYLSLHSYGNYFLLPWGYTSDFPDTYQDMMSVAD 257

Human   339 EAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGI---KYSFTIELRDTGTYGFLLPERY 400
            ...:|| ..|.|..|::|.....||  |..||...:..|:   ..:.|:||...|..||......
  Fly   258 AGAKAI-IYSTNGIYSYGSTYYVLY--PTSGDTTDFAFGVVNATVAMTMELPAAGFQGFDPWISQ 319

Human   401 IKPTCREAFAAVSKIAWHVIR 421
            |:....|::..|..:|..|||
  Fly   320 IERLVTESWVGVRAMAAEVIR 340

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CPB2NP_001863.3 Propep_M14 33..104 CDD:280416 4/10 (40%)
M14_CPB2 119..420 CDD:199868 97/304 (32%)
Substrate binding. /evidence=ECO:0000250|UniProtKB:P00730 181..184 2/2 (100%)