back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CPB1 and CG4017

DIOPT Version :9

Sequence 1:	NP_001862.2	Gene:	CPB1 / 1360	HGNCID:	2299	Length:	417	Species:	Homo sapiens
Sequence 2:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	420	Identity:	147/420 - (35%)
Similarity:	231/420 - (55%)	Gaps:	35/420 - (8%)

- Green bases have known domain annotations that are detailed below.

Human     1 MLALLVLVTV-----ALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ 60
            |..||:|::|     .||..    :.|:..||:||:....|.:..:|.|.:.::      |::..
  Fly     1 MKLLLLLLSVNILIFCLAER----QRFDNYKVYRVSPVKANQLEGLRSLEANSE------DALVL 55

Human    61 IKPH-STVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNV----VEAQFDSRVRATGHSYEKYN 120
            ...| ...||.|..:...|...::|..:|..:::.:|.:..    :|...|:..|:..:|:.:|:
  Fly    56 NNLHLGPTDFLVAPDFDGTFLKLVKDLDLSPELIDANAQTSLSLDIEPIADANRRSDDYSWSEYH 120

Human   121 KWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV----GKAGQNKPAIFMDCGFHAREWI 181
            :......|.|.:..:.|.::|..|.|.::|||.:..|::    |:|  .|.:||::.|.||||||
  Fly   121 ELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRA--EKQSIFLEAGMHAREWI 183

Human   182 SPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCI 246
            .||...:|..|.:.:..:||.  .|.....:|:||..|.|||:||...:|.||||||.. ..:|:
  Fly   184 GPATATYFANELLSSQQQEIM--NLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQ-DKNCV 245

Human   247 GTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMI 311
            |||||||:|..|.|:|||.:||.|:|.||.|.||.|.:.|:.|:::....:..:|::||:||:::
  Fly   246 GTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSFSQLLL 310

Human   312 YPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYD-QGIRYSF 375
            |||.:...|.||:.:|..:....|..:...:||:||.|.....||||||.|.||||. ..::|||
  Fly   311 YPYGHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVKYSF 375

Human   376 TFELRDTGRY----GFLLPESQIRATCEET 401
            |:|||.:| |    ||.||.:||..|.:||
  Fly   376 TYELRPSG-YSFWTGFRLPAAQIIPTGQET 404

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.