DRSC/TRiP Functional Genomics Resources

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Protein Alignment CPB1 and CG3108

DIOPT Version :9

Sequence 1:NP_001862.2 Gene:CPB1 / 1360 HGNCID:2299 Length:417 Species:Homo sapiens
Sequence 2:NP_572262.1 Gene:CG3108 / 31506 FlyBaseID:FBgn0029807 Length:1132 Species:Drosophila melanogaster


Alignment Length:382 Identity:140/382 - (36%)
Similarity:207/382 - (54%) Gaps:27/382 - (7%)


- Green bases have known domain annotations that are detailed below.


Human    22 FEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQN 86
            ::|.:|:|:.|:.:....:..||.|......||     ::|  ..||:.:|.:.....|..::..
  Fly   723 YDGAQVWRIVVQTDKDKRMADELQSKYDGQLWK-----EVK--QEVDYLLKPQVLAAAERHIRAA 780

Human    87 ELQYKVLISNLRNVVE---------AQFDSRVRATGH--SYEKYNKWETIEAWTQQVATENPALI 140
            .|...|||.||:.|:|         |:..:|   .||  :::.|::.|.|..:...:|...|.:.
  Fly   781 NLSRIVLIDNLQRVIEKENPPAEKIAELQNR---KGHRLTWQAYHRLEDIHGFIDYMAKTYPDIC 842

Human   141 SRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTE 205
            |..:||.:.|.|.:.:||:.......|.|::|.|.|||||||||...:...:.|.  |.| .:.|
  Fly   843 STEIIGYSVEKRPLKILKISNGNARNPGIWIDGGMHAREWISPATVTYIANQLVE--GWE-DLPE 904

Human   206 LLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDE 270
            .:..:::|:.||.|.|||.|:.|..|.|||....| |..|.|.|.||||...|...|.|.:||.:
  Fly   905 HMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAH-GRQCPGVDLNRNFGYKWGGKGTSASPCSQ 968

Human   271 TYCGPAAESEKETKALADFIRN-KLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKAT 334
            ||.|..|.||.||..::.||.. ...:.:|||:.|||.|.::||:.|.|:|.::.|:|:.:|:..
  Fly   969 TYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLDRVARQA 1033

Human   335 VKELASLHGTKYTYGPGATTIYPAAGGSDDWAYD-QGIRYSFTFELRDTGRYGFLLP 390
            ...:....|.|||.|..|||:|||||||||||.. .||:|::|.|:.|||||||:||
  Fly  1034 GTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRYGFVLP 1090

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CPB1NP_001862.2 Propep_M14 29..103 CDD:280416 20/82 (24%)
M14_CPB 114..413 CDD:199852 115/281 (41%)
Substrate binding. /evidence=ECO:0000250|UniProtKB:P00730 176..179 2/2 (100%)