Sequence 1: | NP_000667.1 | Gene: | ADORA2B / 136 | HGNCID: | 264 | Length: | 332 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_651772.1 | Gene: | AdoR / 43583 | FlyBaseID: | FBgn0039747 | Length: | 774 | Species: | Drosophila melanogaster |
Alignment Length: | 369 | Identity: | 114/369 - (30%) |
---|---|---|---|
Similarity: | 178/369 - (48%) | Gaps: | 67/369 - (18%) |
- Green bases have known domain annotations that are detailed below.
Human 10 YVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTD 74
Human 75 FYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLT 139
Human 140 PFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIK 204
Human 205 IFLVACRQLQRTELMD-----------------------HSRTTL-------QREIHAAKSLAMI 239
Human 240 VGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKI 304
Human 305 ISRYLLCQADVKS-----------------GNGQAGVQPALGVG 331 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ADORA2B | NP_000667.1 | 7tmA_Adenosine_R_A2B | 8..301 | CDD:320197 | 108/320 (34%) |
TM helix 1 | 9..35 | CDD:320197 | 9/24 (38%) | ||
TM helix 2 | 42..69 | CDD:320197 | 16/26 (62%) | ||
TM helix 3 | 78..108 | CDD:320197 | 16/29 (55%) | ||
TM helix 4 | 122..140 | CDD:320197 | 5/17 (29%) | ||
Agonist binding. /evidence=ECO:0000250 | 173..182 | 2/8 (25%) | |||
TM helix 5 | 179..209 | CDD:320197 | 10/29 (34%) | ||
TM helix 6 | 227..257 | CDD:320197 | 11/29 (38%) | ||
Agonist binding. /evidence=ECO:0000250 | 247..254 | 2/6 (33%) | |||
Agonist binding. /evidence=ECO:0000250 | 266..276 | 2/9 (22%) | |||
TM helix 7 | 269..294 | CDD:320197 | 13/24 (54%) | ||
AdoR | NP_651772.1 | 7tm_4 | 52..>220 | CDD:304433 | 69/185 (37%) |
7tm_1 | 58..334 | CDD:278431 | 98/295 (33%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165150900 | |
Domainoid | 1 | 1.000 | 181 | 1.000 | Domainoid score | I3483 |
eggNOG | 1 | 0.900 | - | - | E33208_3BF5B | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0000536 | |
OrthoInspector | 1 | 1.000 | - | - | otm40873 | |
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR24246 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5322 |
SonicParanoid | 1 | 1.000 | - | - | X919 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 1 | 0.960 | - | - | ||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
10 | 9.830 |