Protein Alignment Lefty1 and scw

DIOPT Version :9

• Sequence 1: NP_034224.1
• Gene: Lefty1 / 13590
• MGIID: 107405
• Length: 368
• Species: Mus musculus
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 390
• Identity: 80/390 - (20%)
• Similarity: 139/390 - (35%)
• Gaps: 110/390 - (28%)

Mouse    23 TGEQILGSLLQQLQLDQPP--VL---DKADVEGMVIPSHVRTQYVALLQHSHASRSRGKRFSQNL 82
            :..:.|..:..::..||.|  ||   .|..::..::.|:...|.:       ||.:....||..|
  Fly    63 SASKFLLEVYNEISEDQEPKEVLHQRHKRSLDDDILISNEDRQEI-------ASCNSILTFSSRL 120

Mouse    83 REVAGRFLVSETSTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPRTALRRQKRLSPHSARARVTI 147
            :.   ..|.:|...| :.|.... :|.:..||||:||::::|            |....||..|:
  Fly   121 KP---EQLDNELDMH-ITFNTND-VPVDLSLVQAMLRIYKQP------------SLVDRRANFTV 168

Mouse   148 EWLR---FRDDGSNRTALIDSRLVSIHESGWKAFDVTEAVNFW---QQLSRPRQPLLLQVSVQRE 206
            ...|   .|.|.|.|  ::.|...:..:.||..|::|:.:.:|   :.|.|..:   |::|:
  Fly   169 SVYRKLDNRQDFSYR--ILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNE---LRISI--- 225

Mouse   207 HLGPGTWSSHKLVRFAAQGTPDGKGQGEPQLELHTL------------------------DLKDY 247
                   ...:|..|||       |...||....:|                        ||:..
  Fly   226 -------GDSQLSTFAA-------GLVTPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKR 276

Mouse   248 GAQGNCDPEAP------VTEGTRCCRQEMYLDLQGMKWAENWILEPPGFLTYECVGSC---LQLP 303
            .|.|...|..|      ......|.|....:|.:.:. ..||::.|..|..|.|.|.|   |...
  Fly   277 RAGGGSPPPPPPPPVDLYRPPQSCERLNFTVDFKELH-MHNWVIAPKKFEAYFCGGGCNFPLGTK 340

Mouse   304 ESLTS----------RWPFLGPRQCVASEMTSLPMIVSVKEGGRTRPQVVSLPNMR---VQTCSC 355
            .:.|:          :.|.|....||.:.:.::.::..:.|      .::.|...:   .:.|.|
  Fly   341 MNATNHAIVQTLMHLKQPHLPKPCCVPTVLGAITILRYLNE------DIIDLTKYQKAVAKECGC 399

Mouse   356  355
              Fly   400  399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lefty1	NP_034224.1	TGFb_propeptide	<106..211	CDD:279078	27/110 (25%)
		TGF_beta	263..355	CDD:278448	20/107 (19%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	53/236 (22%)
		TGFB	300..400	CDD:214556	21/107 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810