Protein Alignment CPA3 and CG4408

DIOPT Version :9

• Sequence 1: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_651141.2
• Gene: CG4408 / 42762
• FlyBaseID: FBgn0039073
• Length: 479
• Species: Drosophila melanogaster
• Alignment Length: 424
• Identity: 132/424 - (31%)
• Similarity: 210/424 - (49%)
• Gaps: 46/424 - (10%)

Human    10 IATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNE-LDFW----YPG--ATHHVAANMMVD 67
            |.|.......|:|..::::|:...|:...:.:.|.:.:: ..|.    .||  .|..|....:.|
  Fly    70 IKTAADSVQARYDHTRIYQVELASEEHVRLFQALEQASDSCSFMGHARQPGQKLTIMVTGAKVAD 134

Human    68 F-----------RVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNN 121
            |           ||.....||:   :|.|  :.|:...|.:.|   :||.|          :|:.
  Fly   135 FDDLVHSYNVTHRVLNYNFQAL---IDAN--YLEVAPEDTKPE---EFDWK----------RYHP 181

Human   122 WEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFC 186
            .|.|.||.:|:.:.:|| |..:::|.:.:..|:..::|...||.|..:|.:.|||||||::||..
  Fly   182 LESINAWLKKLAETHPE-VLLVELGVSAQGRPILGVQIAFDNENRTTVFVESGIHAREWIAPATA 245

Human   187 QWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLN 251
            .:.:.|...:  ::..:..|.....:||.|..|.|||.:::..:|||||||:  ....|.|.|||
  Fly   246 TYIIDQLVNS--KDSAVQALARSQRWYIFPTVNPDGYQYTFKGDRMWRKNRA--LFGICRGVDLN 306

Human   252 RNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHL--NEIKVYITFHSYSQMLLFPY 314
            |||...||....:.|||..:|.|.:..||.||:.:..|||..:  ..|:.:|:.||||||::|||
  Fly   307 RNFPFHWNVTGASGDPCRYDYSGPSAASEVETQRMIEFIRHRVESERIRTFISLHSYSQMIMFPY 371

Human   315 GYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAY-DLGIKHTFAFE 378
            |::::...|:.||..:.|:..:.:.......|..|.|..||||.||.|.|||: .|.|..||::|
  Fly   372 GHSAERVDNYHDLTDIGKLAANKIKDVSGRIYKSGSIYETIYPSSGGSKDWAHGQLKIPITFSYE 436

Human   379 LRDKGKFG--FLLPESRIKPTCRETMLAVKFIAK 410
            ||......  |:|....|:||..|...:::.|.:
  Fly   437 LRGPADSEDLFILSAKEIEPTAAEAFASIQTIVQ 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA3	NP_001861.2	Propep_M14	28..102	CDD:280416	19/91 (21%)
		M14_CPB	114..413	CDD:199852	106/302 (35%)
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416	14/73 (19%)
		M14_CP_A-B_like	179..472	CDD:199844	106/297 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157645
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.750