Protein Alignment CPA3 and CG8539

DIOPT Version :9

• Sequence 1: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_001261520.1
• Gene: CG8539 / 38842
• FlyBaseID: FBgn0035791
• Length: 385
• Species: Drosophila melanogaster
• Alignment Length: 355
• Identity: 93/355 - (26%)
• Similarity: 168/355 - (47%)
• Gaps: 58/355 - (16%)

Human    91 ILIHDLQE--EIEK------QFDVKEDIPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGS 147
            |:::.|.|  |:.:      |.|            .|.:::.|:.:.:::...:...|:...:..
  Fly    14 IVVNQLSEAREVRRRRGLMLQLD------------NYLSYDGIMQYLDELALSHSNRVTLKDVAR 66

Human   148 TVEDNPL--YVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRM 210
            |.|:..|  .::..|:....::.||.|..:|:|||::||.....:::....:..|   :.||...
  Fly    67 TYENRALKMAIITNGDGRPGKRVIFLDAALHSREWMTPAAALLTIHKLVVEFAEN---SDLLTDY 128

Human   211 NFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWN-SIPNTNDPCADNYRG 274
            :::|:|:.|.|||.:|....|.||..|:.| ...|.||:|||||...|| ..|...|||.:||.|
  Fly   129 DWHIMPLANPDGYEYSRNTERYWRNTRTPN-GGNCFGTNLNRNFAVDWNVGFPELKDPCDENYAG 192

Human   275 SAPESEKETKAVTNFIRSHLNEIK---VYITFHSYSQMLLFPYGYTSKLPPN---HEDLAK---- 329
            |:|.||.|.:.|.:.:.. |.|.|   :|::.|:.::.:.:|:.|.:....|   |:::.:
  Fly   193 SSPFSEVEARTVRDIMHG-LVESKRAVMYLSLHTANRSVFYPWVYDTDPVSNQKEHDEIGRFVAD 256

Human   330 --VAKIGTDVLSTRYETRY--IYGPIESTIYPISGSSLDWAYDLGIKHTFAFEL----RDKGKFG 386
              :...||.:.:.:| .:|  .:|          |:|:|:|...|...:|.||:    ||..::.
  Fly   257 RILQSTGTFIKTWQY-AKYAGTFG----------GTSMDYALLAGFPLSFVFEMSGTGRDHVEYK 310

Human   387 FLLPESRIKPTCRETMLAVK-FIAKYILKH 415
            |..|...|:....|:...:| |..|.|.|:
  Fly   311 FFPPARDIRHLAEESWTGIKAFAEKTIEKY 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA3	NP_001861.2	Propep_M14	28..102	CDD:280416	4/12 (33%)
		M14_CPB	114..413	CDD:199852	85/320 (27%)
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	84/312 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157641
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750