Protein Alignment CPA3 and CG8560

DIOPT Version :9

• Sequence 1: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_001261516.1
• Gene: CG8560 / 38830
• FlyBaseID: FBgn0035781
• Length: 418
• Species: Drosophila melanogaster
• Alignment Length: 425
• Identity: 115/425 - (27%)
• Similarity: 215/425 - (50%)
• Gaps: 24/425 - (5%)

Human     1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMM 65
            |..:..|.|:..::|:|...:|..|::.:..::..:..::..|:.....||:....:...::.:|
  Fly     1 MLKLFAVVLLLASVALAVENYDGYKIYDINARNAFEKQLLLRLSGNEAYDFFDLPRSLDASSRVM 65

Human    66 VDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKED--------IPGRHSYAKYNNW 122
                |..::.:..:..|::..::|.::..:..|.:.::.|..::        .....|:..::..
  Fly    66 ----VKPEDQEGFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERSVSFKAFHRH 126

Human   123 EKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKI--GEKNERRKAIFTDCGIHAREWVSPAF 185
            .:|.|:.:::...||..||....|.:.|:..:..:.|  |:....:..:|.|.|||||||::.|.
  Fly   127 AEINAYLDELAAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGIHAREWIAHAG 191

Human   186 CQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDL 250
            ..:.::|..:.:..|   ::||...::.||||.|.|||.:|.|..|||||.| |..:|.|.|||.
  Fly   192 ALYVIHQLVENFAAN---SELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTR-KPISSACYGTDA 252

Human   251 NRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYG 315
            ||||:..|..:..::..|:|.::|....||.||:.:.:.:.|.....|.|:|.|||...||:|:|
  Fly   253 NRNFDFHWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNYLLYPWG 317

Human   316 YTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKH---TFAF 377
            :||.||.:..|..:||:.|.|.:.:...|:|..|...:.:|..:|.|.|:|:  |:.:   :...
  Fly   318 WTSALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYAF--GVANFPVSITM 380

Human   378 ELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYI 412
            || ..|..||....|:|:....||.:.:|.:|:.:
  Fly   381 EL-PAGGTGFNPSTSQIEGFVSETWVGIKAMAQKV 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA3	NP_001861.2	Propep_M14	28..102	CDD:280416	8/73 (11%)
		M14_CPB	114..413	CDD:199852	99/304 (33%)
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	8/72 (11%)
		M14_CP_A-B_like	123..414	CDD:199844	98/297 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157642
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750