Protein Alignment CPA3 and CG18417

DIOPT Version :9

• Sequence 1: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_648119.1
• Gene: CG18417 / 38829
• FlyBaseID: FBgn0035780
• Length: 427
• Species: Drosophila melanogaster
• Alignment Length: 436
• Identity: 135/436 - (30%)
• Similarity: 207/436 - (47%)
• Gaps: 47/436 - (10%)

Human     3 LILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQA--DIIKDLAKT-------NELDFWYPGATH 58
            |.|..||..|.      :::..|::.|..:....|  :.:.:|.|.       :||:...||
  Fly    13 LSLSAGLQRTN------KYEGYKIYEVSSEARSVAFSEALSELVKNASYYEVFSELNAGNPG--- 68

Human    59 HVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDI------PGRHSYA 117
                    ...|...|.......:::|.:.|:|:..::...:.:||:....:      .||....
  Fly    69 --------KIMVHPHEQVNFVQLMEENNVKYDIINRNVGLTLSRQFETNRMLRHWFPYNGRLGTE 125

Human   118 KYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKI--GEKNERRKAIFTDCGIHAREW 180
            :|.|.|:|..:.|.:..::|..|....:|.:.|...|..:.|  |:....:..|..|.|.|||||
  Fly   126 RYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDGGFHAREW 190

Human   181 VSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTK--NRMWRKNRSKNQNS 243
            :|||...:.:.|.  .|........||| .::.||||.|.|||.::...  .|||||.| |..:|
  Fly   191 ISPAAATYLINQL--VYNLEDNADLLLD-FDWVILPVVNPDGYEYTQLSEDTRMWRKTR-KPSSS 251

Human   244 KCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQ 308
            .|||||.||||:..||....::|||.:.|.|:.|.||.|...|.:.|.|:::..::|:|.|||..
  Fly   252 DCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQMYLTLHSYGS 316

Human   309 MLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTI-YPISGSSLDWAYDLGIK 372
            ::|:|:|:|:.:|...|||.:||..|...:.....|.|..||..:|| |..||:|.|:|::.|..
  Fly   317 LILYPWGWTAAVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGASDDYAFNAGFP 381

Human   373 HTFAFELRDKGKFGFLLPESRIKPTCRETMLAV-----KFIAKYIL 413
            .:|..|| ..|..||..|.|.|....:||.:.:     |.|.||.|
  Fly   382 ISFTMEL-PFGGTGFDPPASDIDSIVKETWVGIAAMARKVIQKYPL 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA3	NP_001861.2	Propep_M14	28..102	CDD:280416	13/82 (16%)
		M14_CPB	114..413	CDD:199852	111/308 (36%)
CG18417	NP_648119.1	Propep_M14	<65..99	CDD:280416	7/44 (16%)
		M14_CP_A-B_like	127..420	CDD:199844	107/297 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157640
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750