Protein Alignment CPA3 and CG8562

DIOPT Version :9

• Sequence 1: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_648118.1
• Gene: CG8562 / 38828
• FlyBaseID: FBgn0035779
• Length: 424
• Species: Drosophila melanogaster
• Alignment Length: 428
• Identity: 127/428 - (29%)
• Similarity: 203/428 - (47%)
• Gaps: 30/428 - (7%)

Human     5 LPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFR 69
            |.|..:..||..|...::..:::.|.|....|||::..|: ....||        ::...::...
  Fly     7 LLVLFLGATLVAAEQDYEGYRIYEVIPSTADQADLLHQLS-LQGYDF--------ISETRLLGHP 62

Human    70 ----VSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKE--------DIPGRHSYAKYNNW 122
                ||..:.:..|..::..||...::..:|...|.::|..::        ...||.|..:|...
  Fly    63 SRVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLSTERYYTH 127

Human   123 EKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKI--GEKNERRKAIFTDCGIHAREWVSPAF 185
            |:|:.:.:.:..::|..|....:|.:.|...|..:.|  |:....:|.||.|.|.|||||:|||.
  Fly   128 EEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAA 192

Human   186 CQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGY--IWSWTKNRMWRKNRS--KNQNSKCI 246
            ..:.:.|..:.:..|   ..||...::.|||:.|.|||  ..:.|..|||||.|.  ......|.
  Fly   193 VLYVIDQLVEQFEEN---AHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCY 254

Human   247 GTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLL 311
            |.|.||||:..||....:::||||.|.|....||.||..|.:.:.|..:...:|:|.|||...||
  Fly   255 GADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMYLTLHSYGNYLL 319

Human   312 FPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKHTFA 376
            :|:|:||.||.|.|||..||:.|.:.:.....|.|.||...:.:|..:|:|.|:.|..|...:..
  Fly   320 YPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSIT 384

Human   377 FELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILK 414
            .||...|..||..|.:||.....||.:.::.:|:.:::
  Fly   385 MELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKVIE 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA3	NP_001861.2	Propep_M14	28..102	CDD:280416	15/77 (19%)
		M14_CPB	114..413	CDD:199852	104/304 (34%)
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	15/77 (19%)
		M14_CP_A-B_like	124..420	CDD:199844	103/298 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750