Protein Alignment CPA3 and CG8945

DIOPT Version :9

• Sequence 1: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_573190.1
• Gene: CG8945 / 32693
• FlyBaseID: FBgn0030815
• Length: 1430
• Species: Drosophila melanogaster
• Alignment Length: 476
• Identity: 133/476 - (27%)
• Similarity: 218/476 - (45%)
• Gaps: 87/476 - (18%)

Human    12 TTLAIAP-----VRFDREKVFRVKPQDEKQADIIKDLAKTNE---LDFWYPGATHH------VAA 62
            ||....|     :.:|:.:::|:|||||:|...:::..|..:   |. |..|.:..      |..
  Fly   967 TTTTSRPDVPRRISYDKYQIWRLKPQDEEQVRALEEFKKGEDGVKLQ-WLKGPSLRGLTDVLVPP 1030

Human    63 NMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKED-------------IPGRH 114
            .|:|||          |..|:...:.:|:||.|:.:.|..:. .|||             .|...
  Fly  1031 KMLVDF----------QGTLNYEGIAHEVLIFDVGKAIAYEL-TKEDYLQTTRPSKPRPTAPPPM 1084

Human   115 SYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEK----------------- 162
            ::.:|:|.::||.:.|.:..::|::|..|.||.:.|..||.|:||..|
  Fly  1085 TWNRYHNHDEIVKYLETVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRP 1149

Human   163 NERRK-----AIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIM--TKLLDRMNFYILPVFNV 220
            ..:||     |:|.:.|.....|:.||...|.:.:..:....||..  .:.:....:||:||.|.
  Fly  1150 KRKRKSGQANAVFVEAGAQGLAWIGPAAATWMIAELLRLMKTNKSNEDVEFIRNTTWYIMPVLNP 1214

Human   221 DGYIWSWTKNRMWRKNRSKNQ---------------------NSKCIGTDLNRNFNASWNSIPNT 264
            |||.:|...:|.|:|:||::|                     :..|.|.||:||:...|....::
  Fly  1215 DGYAYSHEYDRFWKKSRSQHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSS 1279

Human   265 NDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNH-EDLA 328
            ..||.:.|.|.||.||.|||||:.|:..:..:||:||:..:|.|::.:|....|...... :|..
  Fly  1280 KAPCNEFYAGPAPFSEPETKAVSEFLMDYRTQIKLYISLQAYGQVISYPVKANSTFNSERLDDFL 1344

Human   329 KVAKIGTDVLSTR-YETRYIYGPIESTIYPISGSSLDW-AYDLGIKHTFAFELRDKGKFGFLLPE 391
            .||.:|||.|..: .::||........|...||.:..: ||::||..::..:|.|.|..|:|||.
  Fly  1345 DVAMVGTDGLRKKGSKSRYKVDASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPS 1409

Human   392 SRIKPTCRETMLAVKFIAKYI 412
            |.|:||.|:....:..:..||
  Fly  1410 SAIEPTARDAFEIISGMLDYI 1430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA3	NP_001861.2	Propep_M14	28..102	CDD:280416	23/82 (28%)
		M14_CPB	114..413	CDD:199852	102/347 (29%)
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416	22/80 (28%)
		M14_CP_A-B_like	1089..1430	CDD:199844	100/340 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820