Protein Alignment CPA3 and CG3108

DIOPT Version :9

• Sequence 1: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_572262.1
• Gene: CG3108 / 31506
• FlyBaseID: FBgn0029807
• Length: 1132
• Species: Drosophila melanogaster
• Alignment Length: 409
• Identity: 132/409 - (32%)
• Similarity: 206/409 - (50%)
• Gaps: 34/409 - (8%)

Human    20 RFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQ 84
            |:|..:|:|:..|.:|...:..:|....:...|       ......||:.:..:...|.:..:..
  Fly   722 RYDGAQVWRIVVQTDKDKRMADELQSKYDGQLW-------KEVKQEVDYLLKPQVLAAAERHIRA 779

Human    85 NKMHYEILIHDLQEEIEKQFDVKEDIP-------GRHSYAKYNNWEKIVAWTEKMMDKYPEMVSR 142
            ..:...:||.:||..|||:....|.|.       .|.::..|:..|.|..:.:.|...||::.|.
  Fly   780 ANLSRIVLIDNLQRVIEKENPPAEKIAELQNRKGHRLTWQAYHRLEDIHGFIDYMAKTYPDICST 844

Human   143 IKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKI----- 202
            ..||.:||..||.:|||...|.|...|:.|.|:|||||:||         ||.||..|::
  Fly   845 EIIGYSVEKRPLKILKISNGNARNPGIWIDGGMHAREWISP---------ATVTYIANQLVEGWE 900

Human   203 -MTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTND 266
             :.:.:..:|:||.||.|.|||.:|.|.:|:|||| .:....:|.|.||||||...|.....:..
  Fly   901 DLPEHMRSINWYIHPVANPDGYEYSHTTDRLWRKN-MRAHGRQCPGVDLNRNFGYKWGGKGTSAS 964

Human   267 PCADNYRGSAPESEKETKAVTNFIRSHLNE-IKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKV 330
            ||:..||||...||.||..::.||.....| .:.|::||||.|.:|:|:||..:|..:..||.:|
  Fly   965 PCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLDRV 1029

Human   331 AK-IGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDL-GIKHTFAFELRDKGKFGFLLPESR 393
            |: .||.:..:. ..:|..|...:|:||.:|.|.|||..: |||:.:..|:.|.|::||:||...
  Fly  1030 ARQAGTSITKST-GVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRYGFVLPARF 1093

Human   394 IKPTCRETMLAVKFIAKYI 412
            |:...::.:.....:|:.|
  Fly  1094 IQYNGKDGVTFADTVARAI 1112

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA3	NP_001861.2	Propep_M14	28..102	CDD:280416	13/73 (18%)
		M14_CPB	114..413	CDD:199852	111/308 (36%)
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	13/73 (18%)
		M14_CP_A-B_like	821..1112	CDD:199844	110/301 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157607
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9821
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.780