Protein Alignment CPA3 and CG3097

DIOPT Version :9

• Sequence 1: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_572259.1
• Gene: CG3097 / 31503
• FlyBaseID: FBgn0029804
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 444
• Identity: 137/444 - (30%)
• Similarity: 230/444 - (51%)
• Gaps: 44/444 - (9%)

Human     1 MRLILPVGLIATTLA-------------IAPVRFDREKVFRVKPQDE---KQADIIKDLAKTNEL 49
            ::|:|.|..:|.:||             ..|.|:|..:::|:....|   |:..:.:.|.:....
  Fly     8 LQLLLLVAAVAASLANELPSNLTLLDANEIPQRYDEAQLWRIYNISEAMQKRVPVGQMLEQKFGG 72

Human    50 DFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIP--- 111
            :.|...       :..:|..::..:.:|.:|.|..:::..:||.|::|..|::  ::.|.|.
  Fly    73 NIWKEN-------SKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDE--ELLEGIQSSS 128

Human   112 ---GRHS---------YAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNE 164
               ||.:         :..|::.|.|.::..::..|:|.:|....||.|.|...|.||:|.|...
  Fly   129 FGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISENPR 193

Human   165 RRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTK 229
            ..|.::.|.|||||||:|||...:.:||....:.......:   .:.:||:||.|.|||.:|.|.
  Fly   194 ENKKVWIDGGIHAREWISPATVTFILYQLMSDWENQPAHIR---GLTWYIMPVMNPDGYEYSRTT 255

Human   230 NRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHL 294
            ||:||||||.::.::|.|.||||||:..||...::.:||:|.||||||.||:||:||..|:....
  Fly   256 NRLWRKNRSPSRRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAKRK 320

Human   295 NEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPIS 359
            ..::.|:|||||.||:::|:.|.:....:...|.:|:.:..:.:..:..|.|........:....
  Fly   321 YNLESYLTFHSYGQMIVYPWAYKAVKVKDASVLQRVSSLAAERILQKTGTSYRAAVTHEVLGIAG 385

Human   360 GSSLDWA-YDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYI 412
            |.|.||: ..||:|:.:..||||:|.:||:||...||.|..|....|:.:|:.|
  Fly   386 GGSDDWSRAALGVKYVYTIELRDRGAYGFVLPPRFIKDTALEGWTVVETVAQAI 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA3	NP_001861.2	Propep_M14	28..102	CDD:280416	14/76 (18%)
		M14_CPB	114..413	CDD:199852	110/309 (36%)
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	11/60 (18%)
		M14_CP_A-B_like	148..439	CDD:199844	109/293 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	244	1.000	Inparanoid score	I3303
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9821
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.800