back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CPA2 and CG8564

DIOPT Version :9

Sequence 1:	NP_001860.2	Gene:	CPA2 / 1358	HGNCID:	2297	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_001261514.1	Gene:	CG8564 / 38825	FlyBaseID:	FBgn0035776	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	336	Identity:	90/336 - (26%)
Similarity:	154/336 - (45%)	Gaps:	51/336 - (15%)

- Green bases have known domain annotations that are detailed below.

Human   123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLK----------------------FST 165
            |...::::|.:..|...:...|....:|.:.|.|.:..|:                      |..
  Fly    54 YLDYKQVNQYLQYLAQRYAHFVHVHILGHTHEKREIRALEINWMNSENVELSPQMREHSPRLFDI 118

Human   166 GGD--------------KPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIF 216
            |.:              :..::::||.|||||::.:|||....::...|.::   ..:|..|...
  Fly   119 GPNGRFTVPVIHVGEHCRKTVFIEAGTHAREWISVSTALNCIYQLTERYTRN---IEVLRKLRFI 180

Human   217 LLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGF-GGPGASSNPCSDSYHGPSA 280
            ::|:.|||||.:|:|||..|||.|.....:..||.|.|||:|..: .||...:.   ::|.|.|.
  Fly   181 IVPLVNPDGYEYSRTKNPKWRKNRRPHKSAKFVGTDCNRNYDIFWNSGPSKINR---NTYKGESP 242

Human   281 NSEVEVKS---IVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRS 342
            .||.|.::   |:|.:.|:  :..|::||||.|.:|:|:||.......:.|||.:|.....:::|
  Fly   243 FSEPETRAMRCILDRMSSN--LLFFLSLHSYGQSIMYPWGYCRDNPIYWRELSSLANSGKSAIKS 305

Human   343 LHGTKYKVGPICSVIYQASGGSIDWSYDYGI-KYSFAFELRDTGR-YGFLLPARQILPTAEETWL 405
            .:|.:|:.|.|..:..:...||: ..|.||: |...|..:....| .||..|...|.....|:|.
  Fly   306 YNGREYRTGSISCLTKRTIAGSV-VDYVYGVLKVPMALVMELPSRELGFQPPVEMISQIGHESWY 369

Human   406 GLKAIMEHVRD 416
            |::.:.:...|
  Fly   370 GIREMCKRSFD 380

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.