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Protein Alignment CPA2 and CG2915

DIOPT Version :9

Sequence 1:	NP_001860.2	Gene:	CPA2 / 1358	HGNCID:	2297	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster

Alignment Length:	392	Identity:	127/392 - (32%)
Similarity:	227/392 - (57%)	Gaps:	13/392 - (3%)

- Green bases have known domain annotations that are detailed below.

Human    34 NEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVL 98
            |:|||:...:||.|.. .|.|.......|:...:.|....|..:...|::..:.:.::..:.|..
  Fly    67 NQEQIELFQKLEEQSD-SLTFIGHAREVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEK 130

Human    99 LDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKF 163
            :|:...|:  ......:...::..:..|:.|.:.:|.:|.::|..|:.:::|||.:...:..:|.
  Fly   131 IDRNLAEV--QPESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKL 193

Human   164 STGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVF 228
            ::..:..||::::|||||||::.|.|.:..|::::  .:||.:..:....:..:.|..|||||.:
  Fly   194 TSNANNKAIFIESGIHAREWISPAAATYIINQLLT--SQDPKVQQLAQDYNWIIFPCVNPDGYKY 256

Human   229 SQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFI 293
            :...:|||||.| ::.|: |.|||.|||:...:...|:||:|....:.||||.||:|.|.::|||
  Fly   257 TFEHDRMWRKNR-QLFGT-CRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELETKRLIDFI 319

Human   294 KSH-GK--VKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICS 355
            ::: ||  :|.:|.||||||:|||||||...::.::|:|.|..:||:.::::.:|..|..|.:..
  Fly   320 RANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKAENGRDYVSGSLFE 384

Human   356 VIYQASGGSIDWSY-DYGIKYSFAFELR--DTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDH 417
            .||.:||||:||:: :.||..::.||||  ...:..|:|||.:|.|||.|.:..::||:|...:.
  Fly   385 TIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPTASEAFTAIRAIVEAAAEK 449

Human   418 PY 419
            .|
  Fly   450 GY 451

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.