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Protein Alignment CPA1 and CG8539

DIOPT Version :9

Sequence 1:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	101/345 - (29%)
Similarity:	167/345 - (48%)	Gaps:	36/345 - (10%)

- Green bases have known domain annotations that are detailed below.

Human    89 MIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYE 153
            ::..|.:.|.|.:|   ..|.|.......||.:|   :.|..:||.|...:.:.|:...:..|||
  Fly    11 LVTIVVNQLSEARE---VRRRRGLMLQLDNYLSY---DGIMQYLDELALSHSNRVTLKDVARTYE 69

Human   154 GRPIYVLKFS--TGGSKRP---AIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTL 213
            .|   .||.:  |.|..||   .|::|..:|||||:|.|:.:....|:..::.::   :.:|...
  Fly    70 NR---ALKMAIITNGDGRPGKRVIFLDAALHSREWMTPAAALLTIHKLVVEFAEN---SDLLTDY 128

Human   214 DIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRN----WDAGFGLSGASSNPCSET 274
            |..:..:.||||:.::.:|.|.||.||:...|: |.|.:.|||    |:.||   ....:||.|.
  Fly   129 DWHIMPLANPDGYEYSRNTERYWRNTRTPNGGN-CFGTNLNRNFAVDWNVGF---PELKDPCDEN 189

Human   275 YHGKFANSEVEVKSIVDFVKDHGNIKA-----FISIHSYSQLLMYPYGYKTEPVPDQDELDQLSK 334
            |.|....||||.:::.|.:  ||.:::     ::|:|:.::.:.||:.|.|:||.:|.|.|::.:
  Fly   190 YAGSSPFSEVEARTVRDIM--HGLVESKRAVMYLSLHTANRSVFYPWVYDTDPVSNQKEHDEIGR 252

Human   335 AAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGR----YGFLLPASQ 395
            .....:....||........|......|:::|:....|...||.||:..|||    |.|..||..
  Fly   253 FVADRILQSTGTFIKTWQYAKYAGTFGGTSMDYALLAGFPLSFVFEMSGTGRDHVEYKFFPPARD 317

Human   396 IIPTAKETWLALLTIMEHTL 415
            |...|:|:|..:....|.|:
  Fly   318 IRHLAEESWTGIKAFAEKTI 337

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.