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Protein Alignment CPA1 and CG18417

DIOPT Version :9

Sequence 1:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_648119.1	Gene:	CG18417 / 38829	FlyBaseID:	FBgn0035780	Length:	427	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	130/434 - (29%)
Similarity:	211/434 - (48%)	Gaps:	57/434 - (13%)

- Green bases have known domain annotations that are detailed below.

Human     4 LLVLSVL-LGAVFGKED-FVGHQVLRI-----SVA-DEAQVQKVKELEDLEHLQLDFWRGPAHPG 60
            :|.||.| |.|...:.: :.|:::..:     ||| .||..:.||.....|..      ...:.|
  Fly     7 ILALSCLSLSAGLQRTNKYEGYKIYEVSSEARSVAFSEALSELVKNASYYEVF------SELNAG 65

Human    61 SPIDVRV-PFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQE------QMFAFRSRARSTDTFN 118
            :|..:.| |...:..|:: :|.:.:.|:.:..:|...|..:.|      ..|.:..|..:...:|
  Fly    66 NPGKIMVHPHEQVNFVQL-MEENNVKYDIINRNVGLTLSRQFETNRMLRHWFPYNGRLGTERYYN 129

Human   119 YATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKR--PAIWIDTGIHSR 181
            :      |||..|::.|..|:|..|....:|.:||||.:..:..:.|.::|  ..|.:|.|.|:|
  Fly   130 H------EEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDGGFHAR 188

Human   182 EWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEI------VTNPDGFAFTH--STNRMWRK 238
            ||::.|:..:...::..:         :.|..|:.|:.      |.||||:.:|.  ...|||||
  Fly   189 EWISPAAATYLINQLVYN---------LEDNADLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRK 244

Human   239 TRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVK---DHGNIK 300
            ||. .:.|.|||.|||||:|..:...|||.:||...|.|....||.|...:.|.:.   |.|.:
  Fly   245 TRK-PSSSDCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQM- 307

Human   301 AFISIHSYSQLLMYPYGYKTEPVPD-QDELDQLSKAAVTALASLYGTKFNYGSIIKAI-YQASGS 363
             ::::|||..|::||:|: |..||| :::|.:::.|..:|:....||.:..|.....| |.|||:
  Fly   308 -YLTLHSYGSLILYPWGW-TAAVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGA 370

Human   364 TIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLAL 407
            :.|:.::.|...|||.|| ..|..||..|||.|....||||:.:
  Fly   371 SDDYAFNAGFPISFTMEL-PFGGTGFDPPASDIDSIVKETWVGI 413

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.