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Protein Alignment CPA1 and CG8562

DIOPT Version :9

Sequence 1:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	128/428 - (29%)
Similarity:	219/428 - (51%)	Gaps:	27/428 - (6%)

- Green bases have known domain annotations that are detailed below.

Human     3 GLLVLSVLLGA--VFGKEDFVGHQVLRI--SVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPI 63
            |||||  .|||  |..::|:.|:::..:  |.||:|.:     |..|.....||.......|.|.
  Fly     6 GLLVL--FLGATLVAAEQDYEGYRIYEVIPSTADQADL-----LHQLSLQGYDFISETRLLGHPS 63

Human    64 DVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEE--QEQMFAFRSRARSTDTFNYATYHTLE 126
            .|.|....::..:..:|:..::...:..::.:.:.||  |.||....:........:...|:|.|
  Fly    64 RVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLSTERYYTHE 128

Human   127 EIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSK--RPAIWIDTGIHSREWVTQASG 189
            ||.:::|.|....|..|....:|.:||.|.:..:..:.|..|  :..|::|.|.|:|||::.|:.
  Fly   129 EIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAV 193

Human   190 VWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTN--RMWRKTRS-HT-AGSLCIG 250
            ::...::.:.:.::|   .:|...|..:..:.|.||:..|.:..  |||||||. :| ||..|.|
  Fly   194 LYVIDQLVEQFEENA---HLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYG 255

Human   251 VDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVE---VKSIVDFVKDHGNIKAFISIHSYSQLL 312
            .|||||:|..:...|||||||::||.|..|.||.|   |:.::..:.|.|.:  ::::|||...|
  Fly   256 ADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIM--YLTLHSYGNYL 318

Human   313 MYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSF 377
            :||:|:.::...:.::||.:::....|:.:..||.:.|||....:|.|:|::.|:.|..|...|.
  Fly   319 LYPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSI 383

Human   378 TFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTL 415
            |.||...|..||..|.::|.....|||:.:..:.|..:
  Fly   384 TMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKVI 421

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.