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Protein Alignment CPA1 and CG8563

DIOPT Version :9

Sequence 1:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_001261515.1	Gene:	CG8563 / 38826	FlyBaseID:	FBgn0035777	Length:	440	Species:	Drosophila melanogaster

Alignment Length:	443	Identity:	134/443 - (30%)
Similarity:	202/443 - (45%)	Gaps:	52/443 - (11%)

- Green bases have known domain annotations that are detailed below.

Human     1 MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLE--HLQLDFWRGPAHPGSPI 63
            :.||.:.:.|.|       :.|:....:...||   ...|.:.||:  ..:||||.  ....|.:
  Fly    16 LAGLGIANNLAG-------YEGYTKYTVQHGDE---NAFKYMVDLQTNDAELDFWL--LTRNSSV 68

Human    64 DVRVPFPSIQAVKIFLESHGISYE--------TMIEDVQSLLDE--------------EQEQMFA 106
            ....|....| .:..|.|.|:|||        ..::...|..|:              ||.:...
  Fly    69 LTVSPRRKTQ-FEASLSSLGVSYEMQPLMELMAALQANSSFADDNYDGEYEECQQDECEQAERPR 132

Human   107 FRSRARSTDTF-NYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRP 170
            .|:|.::...| :|..||   |:..|:..|.|..|.......:|.:.|||.|..|..|.....||
  Fly   133 RRTRRQARGFFSHYPRYH---EVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSISLNSRVRP 194

Human   171 --AIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTN 233
              ..:|....|.|||:|..:.::.|.::..:.   .|||.:|..::|||..:.||||:.:||:|:
  Fly   195 RRVAYIQAATHGREWITTQTVLYLAYELLSNL---RAFTRVLQDVEIFLVPLVNPDGYEYTHTTD 256

Human   234 RMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN 298
            |.|||.|...||..|.|||.|||:...:...|||.|.|||.|.|...|||.|..::|.:::.:.|
  Fly   257 RFWRKNRHRYAGHSCSGVDINRNFGNHWNYQGASQNLCSEVYSGTAPNSEPETSAVVRYLEFNRN 321

Human   299 -IKAFISIHSYSQLLMYPYGYKTEPVPDQ-DELDQLSKAAVTALASLYGTKFNYGSIIKAIYQAS 361
             :|..:.:||:.:.:.|||||....||.. ..|..::..|...:....||::..|:....:|:||
  Fly   322 RVKLSLDVHSFGKFIFYPYGYAKNTVPPTVGTLRSVALRAANQIGRYRGTRYTTGTSASILYEAS 386

Human   362 GSTIDWTYSQ-GIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEH 413
            ||..|:.|.. ||..|:|.||...   .|.:||..||...|||:...:..:.|
  Fly   387 GSLDDFAYGNLGIPLSYTLELPGD---EFHVPAHDIIHVCKETFAGFIEFIRH 436

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.