back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CPA1 and CG8564

DIOPT Version :9

Sequence 1:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_001261514.1	Gene:	CG8564 / 38825	FlyBaseID:	FBgn0035776	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	88/341 - (25%)
Similarity:	152/341 - (44%)	Gaps:	54/341 - (15%)

- Green bases have known domain annotations that are detailed below.

Human   121 TYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFS---------------------- 163
            ||...:::..:|..|.....|.|....:|:|:|.|.|..|:.:
  Fly    53 TYLDYKQVNQYLQYLAQRYAHFVHVHILGHTHEKREIRALEINWMNSENVELSPQMREHSPRLFD 117

Human   164 -------------TGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDI 215
                         .|...|..::|:.|.|:|||::.::.:....::|:.|.::   ..:|..|..
  Fly   118 IGPNGRFTVPVIHVGEHCRKTVFIEAGTHAREWISVSTALNCIYQLTERYTRN---IEVLRKLRF 179

Human   216 FLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASS-NPCSETYHGKF 279
            .:..:.||||:.::.:.|..|||.|.....:..:|.|.|||:|. |..||.|. |  ..||.|:.
  Fly   180 IIVPLVNPDGYEYSRTKNPKWRKNRRPHKSAKFVGTDCNRNYDI-FWNSGPSKIN--RNTYKGES 241

Human   280 ANSEVEVKS---IVDFVKDHGNIKAFISIHSYSQLLMYPYGY-KTEPVPDQDELDQLSKAAVTAL 340
            ..||.|.::   |:|  :...|:..|:|:|||.|.:|||:|| :..|:..: ||..|:.:..:|:
  Fly   242 PFSEPETRAMRCILD--RMSSNLLFFLSLHSYGQSIMYPWGYCRDNPIYWR-ELSSLANSGKSAI 303

Human   341 ASLYGTKFNYGSIIKAIYQA-SGSTIDWTYS-QGIKYSFTFELRDTGRYGFLLPASQIIPTAKET 403
            .|..|.::..|||.....:. :||.:|:.|. ..:..:...|| .:...||..|...|.....|:
  Fly   304 KSYNGREYRTGSISCLTKRTIAGSVVDYVYGVLKVPMALVMEL-PSRELGFQPPVEMISQIGHES 367

Human   404 WLALLTIMEHT--LNH 417
            |..:..:.:.:  |.|
  Fly   368 WYGIREMCKRSFDLRH 383

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.