Protein Alignment CPA1 and CG17633

DIOPT Version :10

• Sequence 1: NP_001859.1
• Gene: CPA1 / 1357
• HGNCID: 2296
• Length: 419
• Species: Homo sapiens
• Sequence 2: NP_609310.2
• Gene: CG17633 / 34297
• FlyBaseID: FBgn0032144
• Length: 430
• Species: Drosophila melanogaster
• Alignment Length: 420
• Identity: 144/420 - (34%)
• Similarity: 235/420 - (55%)
• Gaps: 42/420 - (10%)

Human     6 VLSVLLGAVFGKE--DFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVP 68
            :|:::..|....|  .:..:::.:::..:..|::.:|:||.... .:.|..|....|:.|.:.|
  Fly    11 LLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSD-SIMFLDGVHLVGADIQIIV- 73

Human    69 FPSIQAVKIFLESHG---ISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYD 130
              :...|..|||..|   |.||....|||..|||..|:: |.:.||  |..:|:|.|:.|::.|.
  Fly    74 --APHKVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKV-AIKGRA--TTAYNWAQYYELDDTYA 133

Human   131 FLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG-----GSKRPAIWIDTGIHSREWVTQASGV 190
            :|..|...||.:|:.|:.|.||:||.|..:|.:.|     |..:|.|:::.|||:|||:..|:..
  Fly   134 WLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAAT 198

Human   191 WFAKKITQDYGQDAAFTAILDTLDIFLEIVT-------NPDGFAFTHSTNRMWRKTRSHTAGSLC 248
            :...::         .|:.::.:....|..|       ||||:.:||:|||:|||||  |....|
  Fly   199 FIINQL---------LTSEVENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTR--TPYGSC 252

Human   249 IGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKD-HGNIKAFISIHSYSQLL 312
            .|.||||||...:...||||:.||:||.|..|.||:|..|:..|::. .|.::.::|:|:|||.|
  Fly   253 FGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYL 317

Human   313 MYPYGYKTEPVPDQ-DELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTY-SQGIKY 375
            :||||: |..:||. .:.:::..|::.|:...|||.:..|:|..|||.|:|:::||.| :|.::.
  Fly   318 LYPYGH-TSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRM 381

Human   376 SFTFELRDTGR---YGFLLPASQIIPTAKE 402
            :|.:|||.:..   .||.|||.||:|.::|
  Fly   382 AFCYELRPSSTSYLTGFKLPAEQIVPASEE 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA1	NP_001859.1	Propep_M14	26..100	CDD:460505	22/76 (29%)
		M14_CPA	117..417	CDD:349442	113/304 (37%)
CG17633	NP_609310.2	Propep_M14	33..105	CDD:460505	21/75 (28%)
		Zn_pept	125..407	CDD:214748	109/293 (37%)