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Protein Alignment CPA1 and CG17633

DIOPT Version :9

Sequence 1:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster

Alignment Length:	420	Identity:	144/420 - (34%)
Similarity:	235/420 - (55%)	Gaps:	42/420 - (10%)

- Green bases have known domain annotations that are detailed below.

Human     6 VLSVLLGAVFGKE--DFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVP 68
            :|:::..|....|  .:..:::.:::..:..|::.:|:||.... .:.|..|....|:.|.:.|
  Fly    11 LLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSD-SIMFLDGVHLVGADIQIIV- 73

Human    69 FPSIQAVKIFLESHG---ISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYD 130
              :...|..|||..|   |.||....|||..|||..|:: |.:.||  |..:|:|.|:.|::.|.
  Fly    74 --APHKVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKV-AIKGRA--TTAYNWAQYYELDDTYA 133

Human   131 FLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG-----GSKRPAIWIDTGIHSREWVTQASGV 190
            :|..|...||.:|:.|:.|.||:||.|..:|.:.|     |..:|.|:::.|||:|||:..|:..
  Fly   134 WLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAAT 198

Human   191 WFAKKITQDYGQDAAFTAILDTLDIFLEIVT-------NPDGFAFTHSTNRMWRKTRSHTAGSLC 248
            :...::         .|:.::.:....|..|       ||||:.:||:|||:|||||  |....|
  Fly   199 FIINQL---------LTSEVENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTR--TPYGSC 252

Human   249 IGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKD-HGNIKAFISIHSYSQLL 312
            .|.||||||...:...||||:.||:||.|..|.||:|..|:..|::. .|.::.::|:|:|||.|
  Fly   253 FGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYL 317

Human   313 MYPYGYKTEPVPDQ-DELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTY-SQGIKY 375
            :||||: |..:||. .:.:::..|::.|:...|||.:..|:|..|||.|:|:::||.| :|.::.
  Fly   318 LYPYGH-TSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRM 381

Human   376 SFTFELRDTGR---YGFLLPASQIIPTAKE 402
            :|.:|||.:..   .||.|||.||:|.::|
  Fly   382 AFCYELRPSSTSYLTGFKLPAEQIVPASEE 411

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.