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Protein Alignment CPA1 and CG4017

DIOPT Version :9

Sequence 1:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	146/432 - (33%)
Similarity:	248/432 - (57%)	Gaps:	48/432 - (11%)

- Green bases have known domain annotations that are detailed below.

Human     4 LLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELED-------LEHLQL---DFWRGPAH 58
            ||.:::|:..:..::.|..::|.|:|.....|::.::.||.       |.:|.|   ||...|..
  Fly     7 LLSVNILIFCLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSEDALVLNNLHLGPTDFLVAPDF 71

Human    59 PGSPIDVRVPFPSIQAVKIFLESHGISYETMIE-DVQSLLDEEQEQMFAFRSRARSTDTFNYATY 122
            .|:.:.:      ::.:.:..|....:.:|.:. |::.:.|..           |.:|.::::.|
  Fly    72 DGTFLKL------VKDLDLSPELIDANAQTSLSLDIEPIADAN-----------RRSDDYSWSEY 119

Human   123 HTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKF--STGGSKRPAIWIDTGIHSREWVT 185
            |.|.:.:.::..||.:.|.:||....|.:||||.:..|:.  :.|.:::.:|:::.|:|:|||:.
  Fly   120 HELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHAREWIG 184

Human   186 QASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIV---TNPDGFAFTHSTNRMWRKTRSHTAGSL 247
            .|:..:||.::.....|:     |::....::..:   .||||:.:||.|||||||||| .....
  Fly   185 PATATYFANELLSSQQQE-----IMNLARSYVWYILPHANPDGYVYTHKTNRMWRKTRS-PQDKN 243

Human   248 CIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN-IKAFISIHSYSQL 311
            |:|.|||||||..:...||||:||||:|.|..|.||.||:::..|:|.... :..|:|:||:|||
  Fly   244 CVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSFSQL 308

Human   312 LMYPYGYKTEPVPDQD-ELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYS-QGIK 374
            |:||||: |..:|:.. :|:|:...||.|:...|||::..|::..|||.|:||::||.|. ..:|
  Fly   309 LLYPYGH-TSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVK 372

Human   375 YSFTFELRDTGRY----GFLLPASQIIPTAKETWLALLTIME 412
            ||||:|||.:| |    ||.|||:|||||.:||..:|:.:::
  Fly   373 YSFTYELRPSG-YSFWTGFRLPAAQIIPTGQETTDSLVEMIK 413

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.