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Protein Alignment CPA1 and CG8945

DIOPT Version :9

Sequence 1:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens
Sequence 2:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster

Alignment Length:	454	Identity:	130/454 - (28%)
Similarity:	217/454 - (47%)	Gaps:	71/454 - (15%)

- Green bases have known domain annotations that are detailed below.

Human    23 HQVLRISVADEAQVQKVKELEDLEH-LQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISY 86
            :|:.|:...||.||:.::|.:..|. ::|.:.:||:..|. .||.||...:...:..|...||::
  Fly   984 YQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLRGL-TDVLVPPKMLVDFQGTLNYEGIAH 1047

Human    87 ETMIEDVQSLLDEE---QEQMFAFR-SRARSTD----TFNYATYHTLEEIYDFLDLLVAENPHLV 143
            |.:|.||...:..|   ::.:...| |:.|.|.    |:|  .||..:||..:|:.:...:|.||
  Fly  1048 EVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWN--RYHNHDEIVKYLETVRMRHPQLV 1110

Human   144 SKIQIGNTYEGRPIYVLKFSTGGS------------KRP----------AIWIDTGIHSREWVTQ 186
            ..|.||.::||||:.|:|..:..:            |||          |::::.|.....|:..
  Fly  1111 ELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQGLAWIGP 1175

Human   187 ASGVWFAKKI-----TQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSH---- 242
            |:..|...::     |....:|..|   :.....::..|.||||:|::|..:|.|:|:||.
  Fly  1176 AAATWMIAELLRLMKTNKSNEDVEF---IRNTTWYIMPVLNPDGYAYSHEYDRFWKKSRSQHQTP 1237

Human   243 -TAGSL----------------CIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIV 290
             .:|.|                |.|||.:|||...:|..|:|..||:|.|.|....||.|.|::.
  Fly  1238 PPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFSEPETKAVS 1302

Human   291 DFVKDH-GNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASL--YGTKFNY-- 350
            :|:.|: ..||.:||:.:|.|::.||  .|.....:.:.||.....|:.....|  .|:|..|
  Fly  1303 EFLMDYRTQIKLYISLQAYGQVISYP--VKANSTFNSERLDDFLDVAMVGTDGLRKKGSKSRYKV 1365

Human   351 GSIIKAIYQASGSTIDW-TYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEH 413
            .:....|.|.||....: .|..||.:|:|.:|.|.|.:|:|||:|.|.|||::.:..:..::::
  Fly  1366 DASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTARDAFEIISGMLDY 1429

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.