DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam and dpr20

DIOPT Version :9

Sequence 1:XP_006522949.1 Gene:Dscam / 13508 MGIID:1196281 Length:2034 Species:Mus musculus
Sequence 2:NP_612066.1 Gene:dpr20 / 38101 FlyBaseID:FBgn0035170 Length:525 Species:Drosophila melanogaster


Alignment Length:463 Identity:84/463 - (18%)
Similarity:161/463 - (34%) Gaps:127/463 - (27%)


- Green bases have known domain annotations that are detailed below.


Mouse   289 GSYVCEVSNRYGTAKVIGRL--------YVKQPLKAT-ISPRKVKSSVGSQVSLSCSVTGNEDQE 344
            ||.:.:....|.:..:|..|        ..|.||:.| .:|....:.:.:|||...|...:.|..
  Fly    51 GSGLVQAKTIYDSVNMIQSLDALVEPRETTKVPLQTTPATPPTAHAHIHNQVSTLRSSYEDSDDG 115

Mouse   345 LSWYRNGEILNP-----------------GKNVRITGLNHANLIMDHMVKSDGGAYQCFVRKDKL 392
            :    :|:.:.|                 |:::....|...:..:......|...::......::
  Fly   116 V----DGDYVIPESQTSTVAILDQDSSMKGQDMESLSLQAGSGTVSPKSSPDSSGHKKNASFQQI 176

Mouse   393 SAQDYVQVV------LEDGTPKIISAFSEKVVSPAEPVSLVCNVKGTPLPTVTWTLDDDPILKGS 451
            .:|:...:|      ...|.|   |:.:..:.:|.||    ...:.|.|      :.:..:...|
  Fly   177 GSQNVNALVPATVATTSSGLP---SSSNASLATPTEP----ARNRSTGL------VRNSAVKVDS 228

Mouse   452 GHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGP-----ASIRPMK 511
            .|.:|:...::..:::|:..:.|          :||.      :.......||     ..|....
  Fly   229 KHPLSKGQKTDAPMLNYIFDTFS----------SANK------HHHHDQRYGPHFEDVQRIGQAT 277

Mouse   512 NITAIAGRDTYIHCRVIGYPYYSIKWYK---------NANLLPF-------------NHRQVAFE 554
            |:|..||...:::||:......::.|.:         |.|.|..             ...:..:.
  Fly   278 NLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDKRYKMEFQYP 342

Mouse   555 NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVK----VPPFIQPFEFPRFSIGQRVFI 615
            ||..||:::|:|: ||..|.|.:...|......::||...    |.....|.:...:.|...:.:
  Fly   343 NNWRLKITNVKKD-DEAIYECQISTHPPRVIQINLHVNAPKVMIVDEVGDPLQEKYYEIDSTLQL 406

Mouse   616 PCVVVSGDLPITITWQKDGRPIPASLGVTIDNI---DFT----------------SSLRISNLSL 661
            .|||.:..:..::.:.|.           :|||   |.|                |:|.|:.:|.
  Fly   407 SCVVRNVAMTSSVVFWKH-----------MDNILNYDVTRGGVSVKTELMEDGANSTLSIAKISK 460

Mouse   662 MHNGNYTC 669
            ..:|||||
  Fly   461 TDSGNYTC 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DscamXP_006522949.1 Ig 15..115 CDD:386229
IGc2 239..300 CDD:197706 2/10 (20%)
IG 320..400 CDD:214652 12/96 (13%)
Ig_3 410..488 CDD:372822 12/77 (16%)
IGc2 518..575 CDD:197706 16/78 (21%)
Ig 596..686 CDD:386229 20/93 (22%)
Ig_DSCAM 707..784 CDD:143211
Ig 802..889 CDD:386229
FN3 885..978 CDD:238020
FN3 986..1083 CDD:238020
FN3 1091..1184 CDD:238020
FN3 1189..1278 CDD:238020
Ig_3 1301..1363 CDD:372822
FN3 1380..1470 CDD:238020
FN3 1486..1555 CDD:238020
dpr20NP_612066.1 IG_like 278..365 CDD:214653 20/87 (23%)
Ig 279..378 CDD:299845 20/99 (20%)
Ig 400..471 CDD:299845 19/80 (24%)
IG_like 402..480 CDD:214653 18/78 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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