Sequence 1: | NP_000666.2 | Gene: | ADORA2A / 135 | HGNCID: | 263 | Length: | 412 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_651772.1 | Gene: | AdoR / 43583 | FlyBaseID: | FBgn0039747 | Length: | 774 | Species: | Drosophila melanogaster |
Alignment Length: | 321 | Identity: | 116/321 - (36%) |
---|---|---|---|
Similarity: | 172/321 - (53%) | Gaps: | 41/321 - (12%) |
- Green bases have known domain annotations that are detailed below.
Human 9 YITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAA 73
Human 74 CHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLT 138
Human 139 PMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLA 203
Human 204 ARRQLKQMESQPLPGERAR--------------------------STLQKEVHAAKSLAIIVGLF 242
Human 243 ALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKII 303 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ADORA2A | NP_000666.2 | 7tmA_Adenosine_R_A2A | 7..299 | CDD:320196 | 116/315 (37%) |
TM helix 1 | 8..34 | CDD:320196 | 9/24 (38%) | ||
TM helix 2 | 41..68 | CDD:320196 | 17/26 (65%) | ||
TM helix 3 | 77..107 | CDD:320196 | 14/29 (48%) | ||
TM helix 4 | 121..139 | CDD:320196 | 7/17 (41%) | ||
Agonist binding | 168..177 | 3/8 (38%) | |||
TM helix 5 | 174..204 | CDD:320196 | 13/29 (45%) | ||
TM helix 6 | 226..256 | CDD:320196 | 14/29 (48%) | ||
Agonist binding | 246..253 | 3/6 (50%) | |||
Agonist binding | 264..274 | 2/9 (22%) | |||
TM helix 7 | 267..292 | CDD:320196 | 13/24 (54%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 391..412 | ||||
AdoR | NP_651772.1 | 7tm_4 | 52..>220 | CDD:304433 | 75/181 (41%) |
7tm_1 | 58..334 | CDD:278431 | 107/290 (37%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165150899 | |
Domainoid | 1 | 1.000 | 181 | 1.000 | Domainoid score | I3483 |
eggNOG | 1 | 0.900 | - | - | E33208_3BF5B | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0000536 | |
OrthoInspector | 1 | 1.000 | - | - | otm40873 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_107098 | |
Panther | 1 | 1.100 | - | - | LDO | PTHR24246 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X919 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
9 | 8.740 |