DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dr1 and NC2beta

DIOPT Version :9

Sequence 1:	NP_080382.2	Gene:	Dr1 / 13486	MGIID:	1100515	Length:	176	Species:	Mus musculus
Sequence 2:	NP_609736.1	Gene:	NC2beta / 34875	FlyBaseID:	FBgn0028926	Length:	183	Species:	Drosophila melanogaster

Alignment Length:	171	Identity:	105/171 - (61%)
Similarity:	133/171 - (77%)	Gaps:	0/171 - (0%)

- Green bases have known domain annotations that are detailed below.

Mouse     5 SGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPE 69
            |..||:||:|||:|||:|||.:|.|||||::|||::|||:||||||||||||:||...||||:.|
  Fly    12 SAEDDELTLPRASINKIIKELVPTVRVANESRELILNCCSEFIHLISSEANEVCNMRNKKTINAE 76

Mouse    70 HVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQA 134
            ||::|||.|||..|..|.:.||.:||.||.|||:.|:||||||||||||||||||||||||::||
  Fly    77 HVLEALERLGFHDYKQEAEAVLHDCKEVAAKRRRQSTRLENLGIPEEELLRQQQELFAKAREEQA 141

Mouse   135 ELAQQEWLQMQQAAQQAQLAAASASASTQAGSSQDEEDDDD 175
            ...||:|:.||.||...:...|..|.:::.....|::||||
  Fly   142 REEQQQWMSMQAAAMVQRPPLADGSVASKPSEDDDDDDDDD 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dr1	NP_080382.2	H4	7..130	CDD:304892	86/122 (70%)
		Nuclear localization signal. /evidence=ECO:0000255	100..103		2/2 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	152..176		7/24 (29%)
NC2beta	NP_609736.1	H4	15..135	CDD:304892	84/119 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839268
Domainoid	1	1.000	114	1.000	Domainoid score	I6079
eggNOG	1	0.900	-	-		E1_COG5150
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38809
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3553
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55130
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004284
OrthoInspector	1	1.000	-	-		oto93702
orthoMCL	1	0.900	-	-		OOG6_103431
Panther	1	1.100	-	-	LDO	PTHR46138
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R797
SonicParanoid	1	1.000	-	-		X3019
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790