Protein Alignment CLVS2 and CG10300

DIOPT Version :10

• Sequence 1: NP_001010852.2
• Gene: CLVS2 / 134829
• HGNCID: 23046
• Length: 327
• Species: Homo sapiens
• Sequence 2: NP_651174.2
• Gene: CG10300 / 42798
• FlyBaseID: FBgn0039107
• Length: 311
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 60/280 - (21%)
• Similarity: 117/280 - (41%)
• Gaps: 13/280 - (4%)

Human     8 LSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLL 72
            |.|:....|:.|.||......:.|..::..:...|.:. ..||:..||.|||..:|...|..|..
  Fly     8 LDPKLAALAKSECNEEQAQRAEIIATIKTWITKSPHLK-APTDEQLILAFLRRCRFSQEETKRRF 71

Human    73 AQYFEYRQQNLDMFKSFKATDPGIKQALKDG---FPGGLANLDHYGRKILVLFAANWDQSRYTLV 134
            ..|:..|....::..| :..|..:...|:.|   .|  :..:...|.::::....|.|..:....
  Fly    72 DNYYSLRSVFPEVLGS-RQVDEALLTQLQRGIHVIP--MRPVSPEGPRVIISQFRNIDPKKSNPR 133

Human   135 DILRAILLSLEAM-IEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGI 198
            :..:.|.:.||.: :|.....::|.:.::|..:.|.:|..:..|.:|:.|...:....|.||..|
  Fly   134 EAFKLIFIMLELLALECDNAAISGLIWVVDARDVTMEQMMQYDPFLLKKAFALVDQCIPLRFVEI 198

Human   199 HFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGM--LPPYDMGTW 261
            |.:|.......::..:..||..|...:..:|..: ..|:|.:..:::..|:||.  .....:..|
  Fly   199 HMINMRKEGQTIFNFVTKFLPSKLPFKFVVHKKS-EDLYQHLPRDVMTIEYGGTNGYQAEAVDHW 262

Human   262 ARTLLDHE--YDDDSEYNVD 279
            .:.|||.:  ...|::|..:
  Fly   263 RQKLLDSKDYLAKDAQYGTN 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLVS2	NP_001010852.2	CRAL_TRIO_N	29..75	CDD:215024	12/45 (27%)
		SEC14	101..251	CDD:469559	29/153 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..327
CG10300	NP_651174.2	CRAL_TRIO	112..250	CDD:459890	27/138 (20%)