Protein Alignment CLVS2 and pinta

DIOPT Version :9

• Sequence 1: NP_001010852.2
• Gene: CLVS2 / 134829
• HGNCID: 23046
• Length: 327
• Species: Homo sapiens
• Sequence 2: NP_001287466.1
• Gene: pinta / 42635
• FlyBaseID: FBgn0038966
• Length: 273
• Species: Drosophila melanogaster
• Alignment Length: 268
• Identity: 60/268 - (22%)
• Similarity: 117/268 - (43%)
• Gaps: 16/268 - (5%)

Human    23 NPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFK 87
            :|:.:...:|::.|.::..|.|....|.:.... |||..||....|.:.|..:::.|.:..:.|.
  Fly    18 DPERVLAQVQDLSDWLVANPQINGCNTFENLHF-FLRTSKFDVERAKKKLKTFYQMRAERTEWFD 81

Human    88 SFKATDPGIKQALKDG--FPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIE- 149
            :.....|.|:..||.|  .|.|   .|...|.::|:..|..|...::..::.:...:.|:.:::
  Fly    82 NRDPQLPEIQDLLKLGVFLPIG---PDAEQRMVVVIRTAAHDPKLHSQNNVFKTSKMILDLLLKL 143

Human   150 DPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVI 214
            |||....|.|.|:|........|.::.|.:::.::|. ..::|.:...:.|.|.|.:::......
  Fly   144 DPETCARGMVAILDMQGVQLGHALQMNPKLIKRSVES-WTAYPCQPKLLEFTNAPRHVNFFLNTF 207

Human   215 RPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGM-LPPYDMGTWARTLLDHEYDDDSEYNV 278
            |.|:..|.|.|:|:.....:     :..:.||.|.||. |...::....:.|::...|...|.
  Fly   208 RIFMTPKIRSRLFVRREGTS-----VSCDQLPKELGGQGLSYMELSVKWKQLVEENADFYVEQ-- 265

Human   279 DSYSMPVK 286
            |.|...:|
  Fly   266 DKYKSKLK 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLVS2	NP_001010852.2	CRAL_TRIO_N	29..75	CDD:215024	12/45 (27%)
		SEC14	106..251	CDD:238099	30/145 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..327		60/268 (22%)
pinta	NP_001287466.1	SEC14	87..240	CDD:238099	37/161 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820