Protein Alignment CLVS2 and CG33523

DIOPT Version :9

• Sequence 1: NP_001010852.2
• Gene: CLVS2 / 134829
• HGNCID: 23046
• Length: 327
• Species: Homo sapiens
• Sequence 2: NP_001261457.1
• Gene: CG33523 / 38668
• FlyBaseID: FBgn0053523
• Length: 654
• Species: Drosophila melanogaster
• Alignment Length: 355
• Identity: 67/355 - (18%)
• Similarity: 120/355 - (33%)
• Gaps: 107/355 - (30%)

Human    25 DTLHQDIQEVRDMVITR------------PDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFE 77
            :|..|.|:|:||....:            .||..:|.|..::.|||
  Fly     7 ETTPQQIEELRDRFNRKYASSPPAAPFHPTDIDRIRNDHLWLQRFL------------------- 52

Human    78 YRQQNLDMFKSFKA--------TDPGI---------KQALKDG--FPGGLANLDHYGRKILVLFA 123
             ...:|||..||.:        ...|.         ::.||:|  |   :.|.|..|:.:|| |.
  Fly    53 -EMYDLDMETSFNSLWETCILRQSTGANDIDESELNQEYLKEGSVF---VHNTDVDGKPLLV-FR 112

Human   124 ANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQ 188
            .........|.:::|.::..:|.  ...|..:....:..|.|..:.   :.:....::..:|..:
  Fly   113 VKMHSKSKNLDELIRIVVYWVER--TQREQHLTQLTIFFDMSGTSL---ASMDLEFVKRIVETFK 172

Human   189 DSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGG-- 251
            ..:|.....|......|.::|.:.||:..|..|..:  .|...:...::|.|:.:...:.:||
  Fly   173 QFYPNSLNYILVYELGWVLNAAFKVIKAVLPPKAVE--ILKMISKKDINQYINKDNCLAIWGGED 235

Human   252 -----MLPPYDMGTWARTLL----------DHEYDDDSEYNVDSYSMPVKE--VEK--------- 290
                 .:|.      |:.::          |.::.|.....|||..|.:||  :.|
  Fly   236 NYEFSFVPE------AKKVISKPVAANAGDDDQFADKKVTFVDSAPMVLKETNINKMHTPSEGML 294

Human   291 ELSPKSMKRSQSVVDPTVLKRMDKNEEENM 320
            .::||......|           ||.|..|
  Fly   295 HINPKDFVNFNS-----------KNAEATM 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLVS2	NP_001010852.2	CRAL_TRIO_N	29..75	CDD:215024	12/57 (21%)
		SEC14	106..251	CDD:238099	24/144 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..327		9/45 (20%)
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	27/150 (18%)
		Motile_Sperm	293..396	CDD:279029	7/32 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810