Protein Alignment CLVS2 and CG12926

DIOPT Version :9

• Sequence 1: NP_001010852.2
• Gene: CLVS2 / 134829
• HGNCID: 23046
• Length: 327
• Species: Homo sapiens
• Sequence 2: NP_610510.2
• Gene: CG12926 / 35996
• FlyBaseID: FBgn0033437
• Length: 313
• Species: Drosophila melanogaster
• Alignment Length: 318
• Identity: 80/318 - (25%)
• Similarity: 143/318 - (44%)
• Gaps: 56/318 - (17%)

Human     8 LSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLL 72
            ||||..:||..||.|.||.:.:||:.:|..:..:|.:. .|.|..|::.|||..|:...:....|
  Fly    12 LSPELAKKAHDELGEIPDRIDEDIETLRTWISKQPHLK-ARQDAQFLVAFLRGCKYSLEKTKLKL 75

Human    73 AQYFEYRQQNLDMFKS-------FKATDPG----IKQALKDGFPGGLANLDHYGRKILVLFAANW 126
            ..::..|....:::|:       ....|.|    :.|.|:  ..|...::..||:         :
  Fly    76 DNFYAMRGAVPELYKNRIVGEKQLSILDTGCLLRLPQPLQ--ADGPRIHISRYGQ---------Y 129

Human   127 DQSRYTLVDILRAILLSLEAMI-EDPELQVNGFVLIIDWSN------FTFKQASKLTPSMLRLAI 184
            |..:|::.::::...:..|..| ||....::|||.|||...      |.|...     .:.:||:
  Fly   130 DSKKYSIAEVVQVNTMLGEIQIREDDNAMISGFVEIIDMKGVGAGHLFQFDAV-----LVKKLAV 189

Human   185 EGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEF 249
            .| ..::|.|..|.||||.|.......::.:..:.||.|||..:| :.|:||::.:..|.||:|:
  Fly   190 LG-DKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMSEKIRKRFHIH-SKLDSLYKYVPKECLPAEY 252

Human   250 GGMLPPYD--MGTWARTLLDHE--YDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSV 303
            ||......  :.||...||.::  :::::.|..:               :.::|.|.|
  Fly   253 GGSNGTIQDVVSTWRTKLLAYKPFFEEEASYGTN---------------EKLRRGQPV 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLVS2	NP_001010852.2	CRAL_TRIO_N	29..75	CDD:215024	12/45 (27%)
		SEC14	106..251	CDD:238099	41/151 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..327		3/17 (18%)
CG12926	NP_610510.2	CRAL_TRIO_N	32..77	CDD:215024	12/45 (27%)
		SEC14	117..254	CDD:238099	41/152 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145900
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750