Protein Alignment CLVS2 and CG33514

DIOPT Version :9

• Sequence 1: NP_001010852.2
• Gene: CLVS2 / 134829
• HGNCID: 23046
• Length: 327
• Species: Homo sapiens
• Sequence 2: NP_001014558.1
• Gene: CG33514 / 3346239
• FlyBaseID: FBgn0053514
• Length: 311
• Species: Drosophila melanogaster
• Alignment Length: 299
• Identity: 81/299 - (27%)
• Similarity: 139/299 - (46%)
• Gaps: 25/299 - (8%)

Human     8 LSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLL 72
            |:||..:.|:.:|.|:|:.|..|:|..:..:..:|.:. .|.||.|::.|||..|:....|...|
  Fly     8 LTPELQKVAKEQLKEDPERLEADLQAFKTWIEQQPHLN-PRMDDQFLVAFLRGCKYSLERAKSKL 71

Human    73 AQYFEYRQQNLDMFKSFKATDPGIKQALKDG----FPGGLANLDHYGRKILVLFAANWDQSRYTL 133
            .:|:..:.:..|.|:....||...::..:.|    .|   ..|:..|.:|.:.........:||:
  Fly    72 DKYYTLKTKYPDYFRVTNTTDSKFREIHQTGAIIYLP---TPLNENGPRIGIWRMGLVPVEKYTM 133

Human   134 VDILRAILLSLE-AMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGG 197
            ::.::......| |::||....|||.|.|:|....|.....::||||.:......:::.|.|...
  Fly   134 LECMQVAQAMQEIAILEDDYANVNGVVFIMDMKGATAAHLFQMTPSMAKKFTVFSEEALPLRLKA 198

Human   198 IHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWA 262
            .||:|.......|:.:.:|.:.:|.:.|:|:|||.:..|.:.|..:.||.|:||     :.||..
  Fly   199 QHFINTITGFEQLFNMFKPMMSKKMQSRLFVHGNKMGLLTEQIPLKYLPEEYGG-----ENGTTQ 258

Human   263 RTL------LDHEYDDDSEYNV----DSYSMPVKEVEKE 291
            ..:      || ||.|..:.||    |....|.|.::.|
  Fly   259 DIVAAMEKKLD-EYADFFQENVNFGTDESLRPGKPIDFE 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLVS2	NP_001010852.2	CRAL_TRIO_N	29..75	CDD:215024	13/45 (29%)
		SEC14	106..251	CDD:238099	38/145 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..327		1/5 (20%)
CG33514	NP_001014558.1	CRAL_TRIO_N	28..74	CDD:215024	13/46 (28%)
		SEC14	97..253	CDD:238099	42/163 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145903
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750