Protein Alignment CLVS2 and CG30339

DIOPT Version :10

• Sequence 1: NP_001010852.2
• Gene: CLVS2 / 134829
• HGNCID: 23046
• Length: 327
• Species: Homo sapiens
• Sequence 2: NP_724813.1
• Gene: CG30339 / 246549
• FlyBaseID: FBgn0050339
• Length: 308
• Species: Drosophila melanogaster
• Alignment Length: 309
• Identity: 78/309 - (25%)
• Similarity: 141/309 - (45%)
• Gaps: 47/309 - (15%)

Human     8 LSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKF--------- 63
            ||.|....|..||||..:.:..|::.:||.:..:|.:. .|.||.|::.|||..||
  Fly     7 LSAELRRIAETELNEVEERVPADLKALRDWLAKQPHLR-ARQDDQFLVGFLRGCKFSLEKTKSKL 70

Human    64 -HHFEAFRLLAQYFEYR---QQNLDMFKSFKATDPGIKQALKD--GFPGGLANLDHYGRKILVLF 122
             |.:....|:.:.|..|   ::||.:.:|      |....|..  |..|....|.:|.:
  Fly    71 DHFYTIKTLMPELFGKRLVDERNLILCRS------GTYVRLPKPWGTDGPRLQLTNYEK------ 123

Human   123 AANWDQSRYTLVDILR-AILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEG 186
               :|...:.|:|:.| ..:::.:::.||....::|:|.|:|.:..:....::|..::::.....
  Fly   124 ---FDPKEFKLLDLFRYQTMITEQSIREDDHSNISGYVEIVDMAKMSLSFLAQLDFTLIKRMGIF 185

Human   187 LQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGG 251
            .:.:.|.|..|:|.:|.|....||..:.:..:..|.::|..:: .||..|:::|..|.||.|:||
  Fly   186 AEKAQPTRLKGVHLINCPKEGVALLNLAKSLMPSKLQQRFHVY-KNLEQLNEVIPREYLPEEYGG 249

Human   252 MLPPYDMGTWA-------RTLLDHE--YDDDSEYNVDSYSMPVKEVEKE 291
                 :.|..|       :.||.:|  :.:||:|.||....|.|.|..:
  Fly   250 -----NNGRIADIQAEAEKKLLSYESYFAEDSQYGVDEQLRPGKRVNAD 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLVS2	NP_001010852.2	CRAL_TRIO_N	29..75	CDD:215024	15/55 (27%)
		SEC14	101..251	CDD:469559	33/152 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..327		1/5 (20%)
CG30339	NP_724813.1	CRAL_TRIO_N	28..70	CDD:215024	13/42 (31%)
		CRAL_TRIO	109..249	CDD:459890	33/149 (22%)