DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPSCKMT and CG8067

DIOPT Version :9

Sequence 1:	NP_954584.2	Gene:	ATPSCKMT / 134145	HGNCID:	27029	Length:	233	Species:	Homo sapiens
Sequence 2:	NP_001260960.1	Gene:	CG8067 / 36552	FlyBaseID:	FBgn0033891	Length:	333	Species:	Drosophila melanogaster

Alignment Length:	163	Identity:	31/163 - (19%)
Similarity:	51/163 - (31%)	Gaps:	69/163 - (42%)

- Green bases have known domain annotations that are detailed below.

Human     1 MEGGGGIP----LETLKEESQSRHVLPASFEVNSLQ------KSNW------------------G 37
            :|...|.|    ::.:|:|.|      ..||.|||.      ..:|                  |
  Fly   109 LEQAQGTPGLKMVKLVKDEEQ------LDFEDNSLDLVISSLSLHWVNDLPGCFVRIKQSLKPDG 167

Human    38 FLLTGLVGGTLVAVYAVATPFVTPALRKV--CLPFVPATTKQIENVVKMLRCRRGSLVDIGSGDG 100
            ..:..:.||.  .:|.:.:......|.:.  ..|.:...| ||.::        |||::
  Fly   168 VFIASMFGGD--TLYELRSSLQLAELERKGGISPHISPFT-QIRDI--------GSLLN------ 215

Human   101 RIVIAAAKKGFT---------AVGYELNPWLVW 124
                   :.|||         .:||.....|:|
  Fly   216 -------RAGFTMLTIDTDELVIGYPSMFELMW 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPSCKMT	NP_954584.2	Required for mitochondrial location. /evidence=ECO:0000269\|PubMed:30530489	56..90		5/35 (14%)
ATPSCKMT	NP_954584.2	AdoMet_MTases	83..>188	CDD:388410	10/51 (20%)
CG8067	NP_001260960.1	BioC	58..296	CDD:273953	31/163 (19%)
CG8067	NP_001260960.1	Methyltransf_11	79..170	CDD:285453	13/66 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900