Protein Alignment PPARGC1B and Ppargc1b

DIOPT Version :10

• Sequence 1: XP_011535855.1
• Gene: PPARGC1B / 133522
• HGNCID: 30022
• Length: 1064
• Species: Homo sapiens
• Sequence 2: XP_006525761.1
• Gene: Ppargc1b / 170826
• MGIID: 2444934
• Length: 1046
• Species: Mus musculus
• Alignment Length: 1045
• Identity: 781/1045 - (74%)
• Similarity: 854/1045 - (81%)
• Gaps: 52/1045 - (4%)

Human     1 MAGNDCGALLDEELSSFFLNYLADTQ--------------------------------GGGSGEE 33
            ||||||||||||||||||||||:|||                                ||.||||
Mouse     1 MAGNDCGALLDEELSSFFLNYLSDTQPHCFRCGSGDNCVVLGKHGIAAEDTEACLLDIGGDSGEE 65

Human    34 QLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEALLAELTK 98
            ||.||.|||||||||||||||||||||||||||.|||||:|||||||||||||||||||||.|||
Mouse    66 QLCADLPELDLSQLDASDFDSATCFGELQWCPETSETEPSQYSPDDSELFQIDSENEALLAALTK 130

Human    99 TLDDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLLQKLLLAT 163
            ||||||||||||||||.||.||..|||.|||||.||||||..|:..:||.:||||||||||||||
Mouse   131 TLDDIPEDDVGLAAFPELDEGDTPSCTPASPAPLSAPPSPTLERLLSPASDVDELSLLQKLLLAT 195

Human   164 SYPTSSSDTQKEGTAWRQAGLRSKSQRPCVKADSTQDKKAPMMQSQSRSCTELHKHLTSAQCCLQ 228
            |.||:|||..|:|..|.|..|.|:|||||||.|.|||||.|.:::|||.||||||||||...|.:
Mouse   196 SSPTASSDALKDGATWSQTSLSSRSQRPCVKVDGTQDKKTPTLRAQSRPCTELHKHLTSVLPCPR 260

Human   229 DRGLQPPCLQSPRLPAKEDKEP-GEDCPSPQPAPASPRDSLALGRADP-GAPVSQEDMQAMVQLI 291
            .:...|....||||.:||::|. |||||||.|.||||:||||...|.| .|...:||::||||||
Mouse   261 VKACSPTPHPSPRLLSKEEEEEVGEDCPSPWPTPASPQDSLAQDTASPDSAQPPEEDVRAMVQLI 325

Human   292 RYMHTYCLPQRKLPPQTPEPLPKACSNPSQQVRSRPWSRHHSKASWAEFSILRELLAQDVLCDVS 356
            ||||||||||||||.:.|||:|:|||:.|:||  :|.|||..||.|.||||||||||||:|||||
Mouse   326 RYMHTYCLPQRKLPQRAPEPIPQACSSLSRQV--QPRSRHPPKAFWTEFSILRELLAQDILCDVS 388

Human   357 KPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPKSTGPRPSLRPLRLEVKREVR 421
            ||||||.||||||||:|||||||||||||...:..|||||.|||||||||||||||||||||:|.
Mouse   389 KPYRLAIPVYASLTPQSRPRPPKDSQASPAHSAMAEEVRITASPKSTGPRPSLRPLRLEVKRDVN 453

Human   422 RPARLQQQEEEDEEEEEEEEEEEK-EEEEEWGRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPE 485
            :|.|.:::|:|:|||||||||||| |||||||||||||||||||||||::|||||||||||||||
Mouse   454 KPTRQKREEDEEEEEEEEEEEEEKEEEEEEWGRKRPGRGLPWTKLGRKMDSSVCPVRRSRRLNPE 518

Human   486 LGPWLTFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQIPALESPCE 550
            |||||||.||||      |||||:||..:.:::|.:|||.|  ||.|.:||.:|.||||||||||
Mouse   519 LGPWLTFTDEPL------GALPSMCLDTETHNLEEDLGSLT--DSSQGRQLPQGSQIPALESPCE 575

Human   551 SGCGDMDEDPSCPQLPPRDSPRCLMLALSQSDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPT 615
            |||||.||||||||...|||.||||||||||| :.||||||::|||||||||||||||||||||.
Mouse   576 SGCGDTDEDPSCPQPTSRDSSRCLMLALSQSD-SLGKKSFEESLTVELCGTAGLTPPTTPPYKPM 639

Human   616 EEDPFKPDIKHSLGKEIALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQAG 680
            ||||||||.|.|.|::.|.||||||.|.|.|||||:|||||:|||||||||||:|||.||.||||
Mouse   640 EEDPFKPDTKLSPGQDTAPSLPSPEALPLTATPGASHKLPKRHPERSELLSHLQHATTQPVSQAG 704

Human   681 QKRPFSCSFGDHDYCQVLRPEGVLQRKVLRSWEPSGVHLEDWPQQGAPW-AEAQAPGREEDRSCD 744
            |||||||||||||||||||||..|||||||||||.||||||..|||||. .|.:||.||.:::||
Mouse   705 QKRPFSCSFGDHDYCQVLRPEAALQRKVLRSWEPIGVHLEDLAQQGAPLPTETKAPRREANQNCD 769

Human   745 AGAPPKDSTLLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEE 809
              ...|||..||||||||||||||||||||||.||||||||||||||||||||||||||||.|||
Mouse   770 --PTHKDSMQLRDHEIRASLTKHFGLLETALEGEDLASCKSPEYDTVFEDSSSSSGESSFLLEEE 832

Human   810 EEEGEEEEEDDEEEDSGVSPTCSDHCPYQSPPSKANRQLCSRSRSSSGSSPCHSWSPATRRNFRC 874
            |||.|..|||||.|||||||.||||||||||||||:||||||||||||||.|.|||||||:|||.
Mouse   833 EEEEEGGEEDDEGEDSGVSPPCSDHCPYQSPPSKASRQLCSRSRSSSGSSSCSSWSPATRKNFRR 897

Human   875 ESRGPCSDRTPSIRHARKRREKAIGEGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRR 939
            ||||||||.|||:|||||||||||||||||||:||||||||||||:||||||||.||:||||::|
Mouse   898 ESRGPCSDGTPSVRHARKRREKAIGEGRVVYIRNLSSDMSSRELKKRFEVFGEIVECQVLTRSKR 962

Human   940 GEKYGFITYRCSEHAALSLTKGAALRKRNEPSFQLSYGGLRHFCWPRYTDYDWEGWEVEQKEPAE 1004
            |:|:||||:|||||||||:..||.|||||||||.|||||||||.||||||||...   |:..|:.
Mouse   963 GQKHGFITFRCSEHAALSVRNGATLRKRNEPSFHLSYGGLRHFRWPRYTDYDPTS---EESLPSS 1024

Human  1005 GTQKH 1009
            |..|:
Mouse  1025 GKSKY 1029

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPARGC1B	XP_011535855.1	RRM_PPARGC1B	895..991	CDD:409792	80/95 (84%)
Ppargc1b	XP_006525761.1	RRM_PPARGC1B	918..1014	CDD:409792	80/95 (84%)