Protein Alignment MAP3K8 and Map3k8

DIOPT Version :9

• Sequence 1: NP_001231063.1
• Gene: MAP3K8 / 1326
• HGNCID: 6860
• Length: 467
• Species: Homo sapiens
• Sequence 2: NP_446299.2
• Gene: Map3k8 / 116596
• RGDID: 620969
• Length: 467
• Species: Rattus norvegicus
• Alignment Length: 467
• Identity: 440/467 - (94%)
• Similarity: 455/467 - (97%)
• Gaps: 0/467 - (0%)

Human     1 MEYMSTGSDNKEEIDLLIKHLNVSDVIDIMENLYASEEPAVYEPSLMTMCQDSNQNDERSKSLLL 65
            |||||||||.||||||||.|||||:|:|||||||||||||||||||||||.|||||.|.|:|||.
  Rat     1 MEYMSTGSDEKEEIDLLINHLNVSEVLDIMENLYASEEPAVYEPSLMTMCPDSNQNKEHSESLLR 65

Human    66 SGQEVPWLSSVRYGTVEDLLAFANHISNTAKHFYGQRPQESGILLNMVITPQNGRYQIDSDVLLI 130
            |||||||||||||||||||||||||||||.|||||.|||||||||||||:||||||||||||||:
  Rat    66 SGQEVPWLSSVRYGTVEDLLAFANHISNTTKHFYGCRPQESGILLNMVISPQNGRYQIDSDVLLV 130

Human   131 PWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYG 195
            |||||||:|||.|:|||||||||||||:|||||||||||||||||||||||||||||||||||||
  Rat   131 PWKLTYRSIGSGFVPRGAFGKVYLAQDMKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYG 195

Human   196 AVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIV 260
            |||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 AVLWGDTVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIV 260

Human   261 FMSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTP 325
            ||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||
  Rat   261 FMSTKAVLVDFGLSVQMTEDVYLPKDLRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTP 325

Human   326 PWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALNP 390
            |||||||||||||||||||||||||||||.||||||||||||:|||||||||:||||||||||||
  Rat   326 PWVKRYPRSAYPSYLYIIHKQAPPLEDIAGDCSPGMRELIEAALERNPNHRPKAADLLKHEALNP 390

Human   391 PREDQPRCQSLDSALLERKRLLSRKELELPENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYF 455
            |||||||||||||||.:|||||||||||||||||||||||||||||:|:||||||||||||||||
  Rat   391 PREDQPRCQSLDSALFDRKRLLSRKELELPENIADSSCTGSTEESEVLRRQRSLYIDLGALAGYF 455

Human   456 NLVRGPPTLEYG 467
            |:||||||||||
  Rat   456 NIVRGPPTLEYG 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAP3K8	NP_001231063.1	STKc_MAP3K8	133..388	CDD:270897	245/254 (96%)
Map3k8	NP_446299.2	STKc_MAP3K8	133..388	CDD:270897	245/254 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83690052
Domainoid	1	1.000	488	1.000	Domainoid score	I7652
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3812
Inparanoid	1	1.050	899	1.000	Inparanoid score	I6421
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG39547
OrthoDB	1	1.010	-	-		D159778at32523
OrthoFinder	1	1.000	-	-		FOG0008965
OrthoInspector	1	1.000	-	-		oto142350
orthoMCL	1	0.900	-	-		OOG6_115318
Panther	1	1.100	-	-	LDO	PTHR48016
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6696
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	15.410