Protein Alignment PABPC4L and pab-1

DIOPT Version :9

• Sequence 1: NP_001108206.3
• Gene: PABPC4L / 132430
• HGNCID: 31955
• Length: 370
• Species: Homo sapiens
• Sequence 2: NP_001369814.1
• Gene: pab-1 / 172920
• WormBaseID: WBGene00003902
• Length: 646
• Species: Caenorhabditis elegans
• Alignment Length: 393
• Identity: 218/393 - (55%)
• Similarity: 277/393 - (70%)
• Gaps: 25/393 - (6%)

Human     1 MNVAA--------------------KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQ 45
            |||||                    .|.||||||||||.||.|.:||.|||..|||||||:|||.
 Worm     3 MNVAAPAAAVAGAAAPQPGQNQTGSSYTMASLYVGDLHPDVNESILFEKFSAAGPVLSIRVCRDN 67

Human    46 VTRRSLGYAYVNFLQLADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSID 110
            .||.|||||||||.|.|||::|:|||||:.:.||.:|:||||||..:||||.||:|||||||.||
 Worm    68 ATRLSLGYAYVNFQQPADAERAMDTMNFEALHGKPMRIMWSQRDPAMRRSGAGNIFIKNLDKVID 132

Human   111 NKTLYEHFSAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKN 174
            ||::|:.||.||.|||.||..|:.| ||||.||||:.:.||..||:::||.||.|.|||||:|:.
 Worm   133 NKSIYDTFSLFGNILSCKVAIDEDGFSKGYGFVHFETEEAAQNAIQKVNGMLLAGKKVFVGKFQP 197

Human   175 RKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDS 239
            |..|..||...|.:|||||:||||...:.|.|:.:|:|:|...|.:||| ..|||||||||:|.:
 Worm   198 RAQRNRELGETAKQFTNVYVKNFGDHYNKETLEKLFAKFGNITSCEVMT-VEGKSKGFGFVAFAN 261

Human   240 HEAAKKAVEEMNGRDINGQ--LIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDD 302
            .|.|:.||:.::...|.|.  .:.|.|||||.||.||||:..||.|.||::..|||.||:||||:
 Worm   262 PEEAETAVQALHDSTIEGTDLKLHVCRAQKKSERHAELKKKHEQHKAERMQKYQGVNLYVKNLDE 326

Human   303 TIDDEKLRNEFSSFGSISRVKVMQEE-GQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIAL 366
            |:||:.|:.:|.|:|:|:..|||.:| |:|||||.:||..||:||.|:||||.:::.||||.:|:
 Worm   327 TVDDDGLKKQFESYGNITSAKVMTDENGRSKGFGFVCFEKPEEATSAVTEMNSKMVCSKPLYVAI 391

Human   367 AQR 369
            |||
 Worm   392 AQR 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PABPC4L	NP_001108206.3	RRM	10..>369	CDD:330708	209/362 (58%)
pab-1	NP_001369814.1	PABP-1234	32..640	CDD:130689	211/364 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I4780
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.020