Protein Alignment SCLT1 and Sclt1

DIOPT Version :9

• Sequence 1: XP_016863205.1
• Gene: SCLT1 / 132320
• HGNCID: 26406
• Length: 692
• Species: Homo sapiens
• Sequence 2: NP_001074880.1
• Gene: Sclt1 / 67161
• MGIID: 1914411
• Length: 688
• Species: Mus musculus
• Alignment Length: 692
• Identity: 519/692 - (75%)
• Similarity: 599/692 - (86%)
• Gaps: 4/692 - (0%)

Human     1 MAAEIDFLREQNRRLNEDFRRYQMESFSKYSSVQKAVCQGEGDDTFENLVFDQSFLAPLVTEYDK 65
            ||.|||.||:|..:||:..|::|:|...:..::|.::.:|...||..:.:.:||.|.||:.||:|
Mouse     1 MATEIDLLRDQKDKLNDILRQHQIEHIFRDPTMQNSMSKGGRGDTLVDSINEQSSLPPLIAEYEK 65

Human    66 HLGELNGQLKYYQKQVGEMKLQLENVIKENERLHSELKDAVEKKLEAFPLGTEVGTDIYADDETV 130
            ||.|||.||.||||.:||||||||.||.|||||||:|||||||:|||.|.||.:|.||.||||||
Mouse    66 HLEELNRQLTYYQKHMGEMKLQLETVITENERLHSKLKDAVEKQLEALPFGTGIGNDICADDETV 130

Human   131 RNLQEQLQLANQEKTQAVELWQTVSQELDRLHKLYQEHMTEAQIHVFESQKQKDQLFDFQQLTKQ 195
            |.|||||||||||||.|:|||||.||||..:.|||||||||||||.||::||||||.:||||||:
Mouse   131 RILQEQLQLANQEKTWALELWQTASQELQSVQKLYQEHMTEAQIHEFENRKQKDQLNNFQQLTKK 195

Human   196 LHVTNENMEVTNQQFLKTVTEQSVIIEQLRKKLRQAKLELRVAVAKVEELTNVTEDLQGQMKKKE 260
            |||.|||:|:||..||||||||::.||:|||.||||:|:|||||:||||||.|||.||.||.|||
Mouse   196 LHVANENIEMTNHHFLKTVTEQNMEIEKLRKHLRQARLDLRVAVSKVEELTKVTEGLQEQMLKKE 260

Human   261 KDVVSAHGREEASDRRLQQLQSSIKQLEIRLCVTIQEANQLRTENTHLEKQTRELQAKCNELENE 325
            :|::||.|:|||||||:|||||||||||.||||.|:||:.|:|..::||||.:||||||:|.|||
Mouse   261 EDIMSAQGKEEASDRRVQQLQSSIKQLESRLCVAIEEADVLKTGKSNLEKQIKELQAKCSESENE 325

Human   326 RYEAIVRARNSMQLLEEANLQKSQALLEEKQKEEDIEKMKETVSRFVQDATIRTKKEVANTKKQC 390
            :||||.|||:|||||||||::::|.||||||||.|.||||:|:|:.:|||.|:.:|||.:||||.
Mouse   326 KYEAISRARDSMQLLEEANIKQNQILLEEKQKEVDREKMKKTMSQLIQDAAIKARKEVESTKKQY 390

Human   391 NIQISRLTEELSALQMECAEKQGQIERVIKEKKAVEEELEKPFLQIYREGRGNESDYRKLEEMHQ 455
            .|.||:|.||||.|||:|.||||||:|.|:.|:||||||||    |||||:.:||||||||||||
Mouse   391 EILISQLKEELSTLQMDCDEKQGQIDRAIRGKRAVEEELEK----IYREGKQDESDYRKLEEMHQ 451

Human   456 RFLVSERSKDDLQLRLTRAENRIKQLETDSSEEISRYQEMIQKLQNVLESERENCGLVSEQRLKL 520
            |.|.:|||||||||||..|||||||||.:||||:||..|||||||.||||||||||.||||||||
Mouse   452 RCLAAERSKDDLQLRLKSAENRIKQLEINSSEEMSRSHEMIQKLQTVLESERENCGFVSEQRLKL 516

Human   521 QQENKQLRKETESLRKIALEAQKKAKVKISTMEHEFSIKERGFEVQLREMEDSNRNSIVELRHLL 585
            ||||:||:||||.|||:|||||||||:|:|||||:|||||.||||||||||||||||||||||||
Mouse   517 QQENEQLQKETEDLRKVALEAQKKAKLKVSTMEHQFSIKEHGFEVQLREMEDSNRNSIVELRHLL 581

Human   586 ATQQKAANRWKEETKKLTESAEIRINNLKSELSRQKLHTQELLSQLEMANEKVAENEKLILEHQE 650
            |.|||.||||||||||||||||:||::||||||||||||||||||||||||||||||||||||||
Mouse   582 AAQQKTANRWKEETKKLTESAEMRISSLKSELSRQKLHTQELLSQLEMANEKVAENEKLILEHQE 646

Human   651 KANRLQRRLSQAEERAASASQQLSVITVQRRKAASLMNLENI 692
            |||||||||||||||||||||||||||||||||||:||||||
Mouse   647 KANRLQRRLSQAEERAASASQQLSVITVQRRKAASMMNLENI 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCLT1	XP_016863205.1	None
Sclt1	NP_001074880.1	Smc	180..>509	CDD:224117	239/332 (72%)
		SMC_prok_B	<378..671	CDD:274008	246/296 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83964419
Domainoid	1	1.000	992	1.000	Domainoid score	I1723
eggNOG	1	0.900	-	-		E1_28JSI
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H27031
Inparanoid	1	1.050	993	1.000	Inparanoid score	I5860
Isobase	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG43598
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0010413
OrthoInspector	1	1.000	-	-		oto120835
orthoMCL	1	0.900	-	-		OOG6_109910
Panther	1	1.100	-	-	LDO	PTHR35970
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7857
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	17.260