Protein Alignment SCLT1 and mud

DIOPT Version :9

• Sequence 1: XP_016863205.1
• Gene: SCLT1 / 132320
• HGNCID: 26406
• Length: 692
• Species: Homo sapiens
• Sequence 2: NP_727769.3
• Gene: mud / 44839
• FlyBaseID: FBgn0002873
• Length: 2567
• Species: Drosophila melanogaster
• Alignment Length: 829
• Identity: 174/829 - (20%)
• Similarity: 353/829 - (42%)
• Gaps: 193/829 - (23%)

Human     3 AEIDFLREQNRRL-------------NEDFRRYQMESFS--KYSSVQKAVCQGEGDDTFENLVFD 52
            :.:||::.....|             |..|.|:....|:  :..:..|:...|...:..|::..:
  Fly   734 SHLDFVKRTEIELETKNAQIMAFDEHNNHFDRFLTRIFTLLRSRNCPKSTTMGSATNFLESMHIE 798

Human    53 QSFLAPLVTEYDKHLGELNGQLKYYQKQVGEMKLQLENVIKENERLHSELKDAVEKKLEAFPLGT 117
            :.|      |..:.|  :.|||    ....::|.:|:::..:||.|..:..:.:.|: ..|....
  Fly   799 KRF------ENIEML--IEGQL----LSADDLKRELDDLRSKNEELAKQNINGIIKR-NKFITSL 850

Human   118 EVGTD------IYADDETVRNLQEQLQLAN---QEKTQAVELWQTVSQELDRLHKLYQEHMTEA- 172
            ||.|:      ...::|..:..|:.:||.|   :|::.|.|:    :|.||...:..:::..||
  Fly   851 EVNTEKVKQYITDLEEEAFKRKQKVVQLENTLSKEQSNAKEM----AQRLDIAQQEIKDYHVEAI 911

Human   173 -QIHVFESQKQKDQLFDFQQLTKQLHV-TNENMEVTNQQFLKTVTEQSVIIEQLRKKLRQAKLEL 235
             .|:....:.|:|  |:.....:||.. ..|.:::.:|..:: ..|.|.::|:|.:.  |||||:
  Fly   912 RFINTIRDRLQQD--FNGVNTPQQLGTCMTEFLKMYDQMEVR-YEESSSLVEKLTES--QAKLEM 971

Human   236 RVAVAKVEELTNVTEDLQGQMKKKEKDVV------------------SAHGR--------EEASD 274
            :||..:||.....|....|.:.|:..|.:                  :.|.:        ::..|
  Fly   972 QVAELQVELENKDTNQHSGALIKQLNDTIQNLEKVNAKLSEDNTVSHTVHSKLNESLLKAQKELD 1036

Human   275 RR---LQQLQSSIKQLEIRLCVTIQEANQLRTENTHL-------EKQTRELQAKCNELENERYEA 329
            .|   ::.|::|.:.|.::||......|:|::.:..:       |:|.:.||||| ::|.::.|.
  Fly  1037 LRAKIIENLEASERNLSMKLCELKDLKNKLKSSDEKIAQIKETYEEQIKALQAKC-DMEAKKNEH 1100

Human   330 IVRARNS--MQLLEEA---------NLQKSQALLEEKQK-------------------------- 357
            :.|.:|.  .||.|:|         .|::.||.|:|.|:
  Fly  1101 LERNQNQSLTQLKEDALENCVLMSTKLEELQAKLQEGQQLVDSQKLELDMNRKELALVKSAYEAQ 1165

Human   358 ---EEDIEKMKETVSRFVQDATI---RTKKEVANTKKQCNIQISRLTEELSALQMECAEKQGQ-- 414
               .:|:::.||:..:.|.:..:   :.:||:|:.......| ::|:::|     ||.::.||
  Fly  1166 TKLSDDLQRQKESGQQLVDNLKVELEKERKELAHVNSAIGAQ-TKLSDDL-----ECQKESGQQL 1224

Human   415 -------IERVIKEKKAVEEELE-----KPFLQIYREGRGN---------ESDYRKLEEMHQRFL 458
                   :|:..||...|:..:|     ...||..:|....         :.:.::|.:::..|.
  Fly  1225 VDNLKVELEKERKELAQVKSVIEAQTKLSDDLQREKESAQQLVDNLKVELDKERKELAQVNSAFE 1289

Human   459 VSERSKDDLQLRLTRAENRIKQLETDSSEE------ISRYQEMIQKLQNVLESERENC-GLVSEQ 516
            ...:..||||.:...|:..:..|:.:..:|      ::...|...||.:.|:.|:|:. .||...
  Fly  1290 AQTKLSDDLQRQKESAQQLVDNLKVELDKERKELAQVNSAFEAQTKLSDDLQREKESAQQLVDNL 1354

Human   517 RLKLQQENKQLRKETESLRKIALEAQKKAKVKISTMEHEFSIKERGFEVQLREMEDSNRNSIVEL 581
            :::|.:|.|:|.:.     |..:|||.|....:...:..........:|:|    |..|..:.::
  Fly  1355 KVELDKERKELAQV-----KSVIEAQTKLSDDLQRQKESAQQLVDNLKVEL----DKERKELAKV 1410

Human   582 RHLLATQQKAAN---RWKEETKKLTESAEIRINNLKSELSRQKLHTQELLSQLEMANEKVAENEK 643
            :.::..|.|.::   |.||..::|....:     |..:|.|||...|:|:..|::..:|  |.::
  Fly  1411 KSVIEAQTKLSDDLQRQKESAQQLEAQTK-----LSDDLQRQKESAQQLVDNLKVELDK--ERKE 1468

Human   644 L-----ILEHQEK-ANRLQRRLSQAEERAASASQQLSVITVQRRKAASL 686
            |     ::|.|.| ::.|||:...|::...:...:|.   .:|::.|.:
  Fly  1469 LAQVKSVIEAQTKLSDDLQRQKESAQQLVDNLKMELD---KERKELAQV 1514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCLT1	XP_016863205.1	None
mud	NP_727769.3	SMC_prok_B	319..1178	CDD:274008	97/466 (21%)
		SCP-1	853..1571	CDD:114219	149/697 (21%)
		Smc	1234..>1944	CDD:224117	64/300 (21%)
		DUF948	1392..1517	CDD:295114	31/137 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000