DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC31A1 and CTR2

DIOPT Version :10

Sequence 1:NP_001850.1 Gene:SLC31A1 / 1317 HGNCID:11016 Length:190 Species:Homo sapiens
Sequence 2:NP_012045.3 Gene:CTR2 / 856580 SGDID:S000001218 Length:189 Species:Saccharomyces cerevisiae


Alignment Length:189 Identity:56/189 - (29%)
Similarity:89/189 - (47%) Gaps:29/189 - (15%)


- Green bases have known domain annotations that are detailed below.


Human    10 SYMDSNSTMQPSHHHPTTSASHSH-----GGGDSSMMMMPMTFYFGFKNVELLFSGLVINTAGEM 69
            |.:..:..|...:|....:|.|.|     |.||.: ..|.|.|.:.:||..::|....|.|...:
Yeast    22 SLIGYSKKMDSMNHKMEGNAGHDHSDMHMGDGDDT-CSMNMLFSWSYKNTCVVFEWWHIKTLPGL 85

Human    70 AGAFVAVFLLAMFYEGLKIARESLLRKSQVSIRYNSMPVPGPNGTILMETHKTVGQQMLSFPHLL 134
            ..:.:|:|.||..||.||..    :.|.|:|.|   :.:|..:.|.:.:..|           :.
Yeast    86 ILSCLAIFGLAYLYEYLKYC----VHKRQLSQR---VLLPNRSLTKINQADK-----------VS 132

Human   135 QTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKAVVVDITEH---CH 190
            .::|:.:||..|:.|||:||||||:|.:||..||..|.  :||..:...:|.:.   ||
Yeast   133 NSILYGLQVGFSFMLMLVFMTYNGWLMLAVVCGAIWGN--YSWCTSYSPEIDDSSLACH 189

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC31A1NP_001850.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35 6/29 (21%)
Bis-His motif. /evidence=ECO:0000269|Ref.24 5..6
Methionine segments (Mets) motif. /evidence=ECO:0000269|Ref.24 7..12 1/1 (100%)
Ctr 45..175 CDD:461194 41/129 (32%)
CTR2NP_012045.3 Ctr 61..166 CDD:461194 38/122 (31%)
Blue background indicates that the domain is not in the aligned region.

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