| Sequence 1: | NP_001186662.1 | Gene: | Daxx / 13163 | MGIID: | 1197015 | Length: | 740 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001285675.1 | Gene: | Daxx / 33906 | FlyBaseID: | FBgn0031820 | Length: | 1659 | Species: | Drosophila melanogaster |
| Alignment Length: | 604 | Identity: | 151/604 - (25%) |
|---|---|---|---|
| Similarity: | 238/604 - (39%) | Gaps: | 148/604 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 1 MATD-----------------DSIIVLDDDDEDEAAAQP----GPSNLPP--NPASTGPGPGLSQ 42
Mouse 43 QATGLSEPRVDGGSSNSGSRKCYKLDNEKLFEEFLELCK-TETSDHPE--VVPFLHKLQQRAQSV 104
Mouse 105 FLASAEFCNILSRVLARSRKRPAKIYVYINELCTVLKAHSIKKKLNLAPAASTTSEASGPNPPTE 169
Mouse 170 ----PPSDLTNTE------------------------------NTASEASRTRGSRRQIQRLEQL 200
Mouse 201 LALYVAEIRRLQEKELDLSELDDPDSSYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPY 265
Mouse 266 RGTRYPEVNRRIERLINKPGLDTFPDYGDVLRAVEKAATRHSLGLPRQQLQLLAQDAFRDVGVRL 330
Mouse 331 QERRHLDLIYNFGCHLTDDYRPGVDPALSDPTLARRLRENRTLAMNRLDEVISKYAMMQDKTEEG 395
Mouse 396 ERQKRR--------------ARLLGTAPQPSDPPKASSESGEGPSGMASQECPTTSKAE------ 440
Mouse 441 ---------TDDDDDDDDDDDDED--------NEESEEEEEEEEEEKEATED---------EDED 479
Mouse 480 LEQLQEDQGGDEEEEGGDN 498 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Daxx | NP_001186662.1 | Necessary for interaction with USP7 and ATRX. /evidence=ECO:0000250 | 1..166 | 41/190 (22%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..60 | 18/81 (22%) | |||
| Daxx | 56..150 | CDD:367454 | 20/96 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 155..191 | 11/69 (16%) | |||
| Interaction with histone H3.3. /evidence=ECO:0000250 | 189..423 | 81/247 (33%) | |||
| DAXX_histone_binding | 189..393 | CDD:240523 | 71/203 (35%) | ||
| Nuclear localization signal. /evidence=ECO:0000255 | 391..395 | 0/3 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 612..689 | ||||
| Nuclear localization signal. /evidence=ECO:0000255 | 623..629 | ||||
| Interaction with SPOP. /evidence=ECO:0000250 | 627..740 | ||||
| Sumo interaction motif (SIM). /evidence=ECO:0000250 | 733..740 | ||||
| Daxx | NP_001285675.1 | PTZ00449 | <278..>379 | CDD:185628 | |
| PRK10263 | <707..>892 | CDD:236669 | |||
| DAXX_histone_binding | 1276..1462 | CDD:240523 | 68/199 (34%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167837846 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_28JDB | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0007192 | |
| OrthoInspector | 1 | 1.000 | - | - | oto92960 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_108716 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR12766 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5527 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 9 | 8.730 | |||||