Protein Alignment KLF6 and cbt

DIOPT Version :10

• Sequence 1: NP_001291.3
• Gene: KLF6 / 1316
• HGNCID: 2235
• Length: 283
• Species: Homo sapiens
• Sequence 2: NP_722636.1
• Gene: cbt / 33224
• FlyBaseID: FBgn0043364
• Length: 428
• Species: Drosophila melanogaster
• Alignment Length: 231
• Identity: 79/231 - (34%)
• Similarity: 115/231 - (49%)
• Gaps: 45/231 - (19%)

Human    60 QEDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELSP--T 122
            :.::|..:.....:|..:|:.:   ||..|..:|  ...|.|....::...|     ||:.|  |
  Fly   152 EANVWRNLKFKMNRKRAAEVAL---PPVQTPETP--VAKLVTPPAPAECIKE-----EEIKPILT 206

Human   123 AKFTSDPIGE-----VLVSSGKLSSSVTSTP-PSSPELSREPSQLWGCVPGELPSPGKVRSGTSG 181
            ..:.| |:..     :|:|:  :::..:.|| |.:|.:|.|
  Fly   207 PIYVS-PVASSASQLILLST--VAAQQSPTPVPKTPTMSEE------------------------ 244

Human   182 KPGDKGNGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDE 246
            |...:.....:...|.|::.|.|..|.|.|.||||||||||.||||:|:.|.||.|:.||:||||
  Fly   245 KLTTRITAAQAAATRSRIYECSFPDCGKNYFKSSHLKAHQRVHTGERPFICKWENCDKRFSRSDE 309

Human   247 LTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRH 282
            |:||.|.|||.|.|:||.|.:.|.|||||:.|:|||
  Fly   310 LSRHKRTHTGEKKFQCSVCQKKFMRSDHLSKHVKRH 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLF6	NP_001291.3	KLF6_N	2..201	CDD:409245	27/148 (18%)
		9aaTAD, inactive. /evidence=ECO:0000269|PubMed:31375868	62..70		1/7 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..198		17/99 (17%)
		COG5048	177..>265	CDD:227381	44/87 (51%)
		C2H2 Zn finger	205..224	CDD:275368	13/18 (72%)
		C2H2 Zn finger	232..254	CDD:275368	14/21 (67%)
		zf-C2H2	260..282	CDD:395048	12/21 (57%)
		C2H2 Zn finger	262..282	CDD:275368	11/19 (58%)
cbt	NP_722636.1	C2H2 Zn finger	265..287	CDD:275368	15/21 (71%)
		COG5048	<270..362	CDD:227381	50/76 (66%)
		C2H2 Zn finger	295..317	CDD:275368	14/21 (67%)
		zf-H2C2_2	309..332	CDD:463886	13/22 (59%)
		C2H2 Zn finger	325..345	CDD:275368	11/19 (58%)