Protein Alignment FAM43A and CG42673

DIOPT Version :10

• Sequence 1: NP_710157.2
• Gene: FAM43A / 131583
• HGNCID: 26888
• Length: 423
• Species: Homo sapiens
• Sequence 2: NP_729510.1
• Gene: CG42673 / 39111
• FlyBaseID: FBgn0261555
• Length: 904
• Species: Drosophila melanogaster
• Alignment Length: 523
• Identity: 97/523 - (18%)
• Similarity: 168/523 - (32%)
• Gaps: 194/523 - (37%)

Human    39 ARACPEGALSR----VGSMFRSKRK-KLHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKI-- 96
            |.:.||....|    ||..|....| .||..|.:|                .|..:|::..::
  Fly   347 ATSDPESQAMRIVRTVGQAFEVCHKFNLHKNSLEP----------------NDERSDISSSELLD 395

Human    97 ------WSKSEAGRQG-------TKMKLTVSAQGIRMVHAEERALRRPGHLYLL--------HRV 140
                  ...||.|.:|       .|..|.::..   :.|.:.   :||.||.::        ...
  Fly   396 VEQISEQQLSEDGERGGGDNETPKKEHLAITPD---LNHTQP---QRPNHLDIMPSHSSLRKSNS 454

Human   141 TYCVADAR------LPKVFAWVYRHELKHKAVMLR--------CHAVLVSKPE---KAQAMALLL 188
            ..|..|.:      .|:......:.:|:.:|:..|        ....|:|:..   :|||....|
  Fly   455 LLCDVDDKSPGSPSSPRSEITQLKDQLEAQALQTRQALGQLMLVREQLISETNARIEAQARTQQL 519

Human   189 YQTSANALAEFKRLKRRDDARHQQQELVG--AHTIPLVPLR---KLLLHGPCCYKPPVERSRSAP 248
            .|.:...|.....|     ..:.:|:..|  :..|.:.|.:   ::||............::...
  Fly   520 LQQNRELLEHLASL-----GAYNEQQTAGLTSANIGMAPQQSQLQMLLQATSNNNNLATINQQIS 579

Human   249 KLGSITEDL--LGEQL---------------EQELQEEEEEEQPEGCPEEEENRAAEGDPA---- 292
            .||||.:.|  |..||               :|:.|::::::|.:..|     .||...||
  Fly   580 NLGSINQQLTSLSHQLSGLNQQSQHLQNLQQQQQQQQQQQQQQTQAAP-----TAATPPPAAGGS 639

Human   293 ------------------EEEAEAQRALVVAMHFECGDLLDTLE-------NGRGEA-------- 324
                              :::.:.|.||...:.....:||:.|:       .|:.:.
  Fly   640 SPYPSMSALQSISNQLQQQQQQQQQDALSKDLFQVNQELLNRLQALNLNANPGQSQPTPSATAHN 704

Human   325 ------------------LGGGGG---SLGPGA----GPPPL-------LLGSAS---DMKAELS 354
                              .||.||   ...|.|    .|.||       ..||:|   |::..:.
  Fly   705 SFFYVNPLSCTPATPNNNAGGAGGFNFLTSPAATGTLTPSPLGTMNRNSFAGSSSLNEDIRLSIE 769

Human   355 QLISDLGELSFGNDVRTLQADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASADE 419
            |.:::|.|                 :|.:..|.|:.:.:..||..:|..|:..||      :.|.
  Fly   770 QNLNNLEE-----------------QLKAAVSNGNLAGLACGGSTSTRDTSRSSS------TLDS 811

Human   420 PHS 422
            |.|
  Fly   812 PSS 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAM43A	NP_710157.2	PID_2	69..256	CDD:405418	38/231 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	263..298		8/56 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..344		9/62 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	382..423		11/41 (27%)
CG42673	NP_729510.1	PH-like	<352..386	CDD:473070	11/49 (22%)