DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dapk2 and CG10177

DIOPT Version :9

Sequence 1:	XP_036010488.1	Gene:	Dapk2 / 13143	MGIID:	1341297	Length:	490	Species:	Mus musculus
Sequence 2:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	70/287 - (24%)
Similarity:	135/287 - (47%)	Gaps:	20/287 - (6%)

- Green bases have known domain annotations that are detailed below.

Mouse     3 QASMRSPNMETFKQ----QKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASR 63
            |..:.|..:|:.|.    :.::.:.:..|.:......::.:.:.::...:...|.:.| |::::.
  Fly   125 QHHLDSGTLESMKSHDLPEAIQLYIETIEPVEHNTRTLIYRGQTRANRTKCTVKMVNK-QTQSND 188

Mouse    64 RGVCREEIEREVSILRQV-LHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEAT 127
            ||    :...|..:|||: .|||||.|....|:...:..:||.:. ..:...:.::..|||.:|.
  Fly   189 RG----DTYMEAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLD-CNMQKVIQKRGILSEADAR 248

Mouse   128 SFIKQILDGVNYLHTKKIAHFDLKPENIMLLDK----NIPIPHIKLIDFGLAHEIEDGVEFKNIF 188
            |.::..:..:.::|..::.|.|:||||:::...    |..:  :|:.:|.||.... |.:.....
  Fly   249 SVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKM--VKVANFDLATYYR-GSKLYVRC 310

Mouse   189 GTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTK--QETLANITAVSYDFDEEFF 251
            |||.::|||::.......:.|.||:||..:.:|.|..||....|  :|..|.|.:....:.::..
  Fly   311 GTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDME 375

Mouse   252 SQTSELAKDFIRKLLVKETRKRLTIQE 278
            |..|..|...|..|||.:...|:.|.|
  Fly   376 SVMSPEATQLIDGLLVSDPSYRVPIAE 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dapk2	XP_036010488.1	STKc_DAPK2	17..285	CDD:271098	66/269 (25%)
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	65/248 (26%)
		PKc_like	164..403	CDD:304357	65/248 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900