Protein Alignment Cyp4b1 and Cyp4e1

DIOPT Version :10

• Sequence 1: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Sequence 2: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Alignment Length: 539
• Identity: 161/539 - (29%)
• Similarity: 264/539 - (48%)
• Gaps: 84/539 - (15%)

Mouse    21 ILMVTVLKLLSLLFRRQKLARALDSFPGPPKHWLFGHALEIQKTGG--LDKVVTW-----TEQFP 78
            :.:||..: |.||.|:    |.|:.|.||....|.|:|.::..|..  |::...|     .:.|.
  Fly    13 LFLVTYFE-LGLLRRK----RMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWWHEYGKDNFR 72

Mouse    79 YAHPLWLGQFIVFLNIYEPDY------AKAVYSRGDPKAAYVYDFFLQWIGKGLLVLEGPKWFQH 137
            |    |:|.:...: :..|.|      ::.:.|:.|     |||....|:|.|||...|.||.:|
  Fly    73 Y----WIGYYSNIM-VTNPKYMEFILSSQTLISKSD-----VYDLTHPWLGLGLLTSTGSKWHKH 127

Mouse   138 RKLLTPGFHYDVLKPYVAIFAESTRVMLDKWEKKASENKSFDIFCDVGHMALDTLMKCTFGKGDS 202
            ||::||.||:::|:.:..:..|::...:|:.:|.|.....||...:..::.||.:.....|...:
  Fly   128 RKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVSIN 192

Mouse   203 GLSHSDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLTPHGRRFLRACQIAHDHTDHVIRQ---- 263
            .:.:..:|...|..|:|..::.|..|....|.:::...|....:.:..:...|.|:.:|.:
  Fly   193 AMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEV 257

Mouse   264 RKAALQ-----DEKEQKKLQERRHLDFLDILLGARDESGIKLSDADLRAEVDTFMFEGHDTTTSG 323
            ||:.|:     ||..:||:.      |||.||.::.: |..|:..:|..||.|||||||||||||
  Fly   258 RKSGLEVGIKADEFSRKKMA------FLDTLLSSKVD-GRPLTSQELYEEVSTFMFEGHDTTTSG 315

Mouse   324 ISWFLYCMALYPMHQQRCREEVREILG----DRD-SFQWDDLAQMTYLTMCMKECFRLYPPVPQV 383
            :.:.:|.::.:|..|::...|..:::|    .|| :||  :::.|.:|.:.:||..||||.||.:
  Fly   316 VGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQ--EISTMKHLDLFIKEAQRLYPSVPFI 378

Mouse   384 YRQLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVWPDPEVFDPLRFSPENMTGRHPFAFMPFSA 448
            .|...|... :||..:|.|:.::|.:..|..|..|:.||..|.|.||..|.   ..||.::||||
  Fly   379 GRFTEKDYV-IDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREK---PGPFEYVPFSA 439

Mouse   449 GPRNCIGQQFAMNEMKVVTALCLLRFEFSPDPSKI-----------------------------P 484
            ||||||||:||:.|:|.|.:..:..||..|...::                             |
  Fly   440 GPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDP 504

Mouse   485 IKVPQLILRSKNGIHLYLK 503
            |....:.|:|:||:||.:|
  Fly   505 ILSASMTLKSENGLHLRMK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4b1	NP_031849.1	CYP4B-like	67..501	CDD:410771	144/487 (30%)
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	141/474 (30%)