Protein Alignment Cyp4b1 and Cyp4d8

DIOPT Version :9

• Sequence 1: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Sequence 2: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 543
• Identity: 164/543 - (30%)
• Similarity: 265/543 - (48%)
• Gaps: 116/543 - (21%)

Mouse    29 LLSLLF------------RRQKLARALDSFPGP----------------PK-------------- 51
            |:.|||            ||:|:|    :.|||                ||
  Fly     6 LVVLLFGAGWIIHLGQADRRRKVA----NLPGPICPPLIGAMQLMLRLNPKTFIKVGREYVLKFG 66

Mouse    52 H----WLFGHALEIQKTGGLDKVVTWTEQFPYAHPLWLGQFIVFLNIYEPDYAKAVYSRGDPKAA 112
            |    |:|...|.:.....|::.:..:::....||
  Fly    67 HLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHP------------------------------ 101

Mouse   113 YVYDFFLQWIGKGLLVLEGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRVMLDKWEKKASENKS 177
             ||....||:|.|||:.:|..|.|.||::||.||:.:|:.:|.:|.:.:.:.:.:..:||:.| :
  Fly   102 -VYKVLGQWLGNGLLLSDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGN-T 164

Mouse   178 FDIFCDVGHMALDTLMKCTFGKGDSGLSHSDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLT-P 241
            ||::..:...|||.:.:...|......::....|..||::.|.|:..|..|.....:.::.|| |
  Fly   165 FDVYRSICAAALDIIAETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHP 229

Mouse   242 HGR----RFLRACQIAHDHTDHVIRQRKAALQDEKEQKKLQE--------RRHLDFLDILLGARD 294
            |.:    :.:|..|   :.|..||.:|:.||:|  :|.||.:        :|.:..||:||.:..
  Fly   230 HLKWRQTQLIRTMQ---EFTIKVIEKRRQALED--QQSKLMDTADEDVGSKRRMALLDVLLMSTV 289

Mouse   295 ESGIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMHQQRCREEVREILG-DRD---SF 355
            : |..|::.::|.|||||||||||||||.:|:.|:.::.:|..|.:..||:.::|| ||.   |.
  Fly   290 D-GRPLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSI 353

Mouse   356 QWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSKPVTFV-----DGRSLPAGSLISLHIYALHRN 415
            :  ||.::.|:...:||..|:|||||.|.|:|.....:.     || .:||||.|.:.|:.:||.
  Fly   354 R--DLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDG-VIPAGSEIIIGIFGVHRQ 415

Mouse   416 SAVWPDPEVFDPLRFSPENMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSPDP 480
            ...:|:|:.|.|.|.  ||.:...||..:||||||||||||:||..|||::.|..:..:|..|..
  Fly   416 PETFPNPDEFIPERH--ENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMG 478

Mouse   481 SKIPIKVPQLILRSKNGIHLYLK 503
            .::.. :..::|||:.|..|.::
  Fly   479 QRVEC-IVNIVLRSETGFQLGMR 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4b1	NP_031849.1	p450	47..500	CDD:278495	155/508 (31%)
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	150/474 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845251
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750